#transplantaion

Liver is one of the most important organs of the human digestive system. Liver disorders encompass mild to severe ones. When no other medication and treatment can fix your condition, liver transplantation becomes the last and only treatment option. Most times, complete liver failure is what demands a liver transplantation.

Liver failure is that stage when most of the liver gets damaged and is beyond the scope of any possible repair. Such a liver stops functioning and this leads to a life-threatening situation that requires immediate medical attention. Liver failure is not an overnight disease. This occurs gradually and over a period of multiple years.

Causes of Liver failure which calls for liver transplantation: Viral attack: Hepatitis viruses like, A B, C, etc. can infect the liver, which if not treated at the appropriate time will lead to liver failure. Alcohol poisoning: Regular and long-term alcohol abuse may lead to liver failure Cirrhosis: Severe scarring of the liver (due to toxins that affect the liver) is known as liver cirrhosis. This is usually the last stage of any severe liver disease and liver transplantation is the only cure for it. Hemochromatosis or iron overload: This is a genetic disorder that causes damage to the liver by absorption of excessive iron. Infectious mononucleosis: Another viral disease caused by the EBV virus. Extreme cases of this disease can cause severe liver damage (rare).

Symptoms of liver failure that prompts liver transplant: Defective fat metabolism: This includes increased levels of LDL and triglycerides, fat deposition in other organs, obesity, fatty lumps on the skin, excessive fat deposition in the upper abdomen area, fatty liver, etc. Frequent digestive disorders: Pain in the liver area, irritable bowel syndrome, gall bladder diseases, indigestion problems, bloating in the abdomen, intolerance to alcohol and fatty foods, nausea and vomiting, etc. Physical signs and symptoms: rashes and itchy skin, yellow eyes, bad breath, discolored tongue, sweating and bad body odor, brown blemishes on the skin, etc. Other symptoms: a headache, mood swings, increased body heat, depression, unstable blood sugar levels, fatigue, allergies, etc. Non-alcoholic steatohepatitis (NASH): Fat deposition in liver cells results in inflammation that scars the liver. Risk factors for this disease include diabetes, high cholesterol, and obesity. Treatment for liver damage: Liver transplant Liver transplantation involves replacement of a damaged liver with a part of a liver or a new and complete healthy liver from a donor. This is a major surgery and requires proper post-operative treatment and care for quick recovery.

After a liver transplantation, the first three months require critical attention and supportive medication.  Some of the doses of medication are determined according to the weight of the patient.

Some of the most common medications that are prescribed after a liver transplant include: Cyclosporin, Tacrolimus, Prednisone, Azathioprine, Sirolimus, Acyclovir, etc. Primarily the medication regime includes drugs like immunosuppressant, antibiotics and antiviral medicines to treat/prevent organ rejection and further infections respectively.

The mission of World Kidney Day is to raise awareness of the importance of our kidneys to our overall health and to reduce the frequency and impact of kidney disease and its associated health problems worldwide.

The objectives are the following:

·         Raise awareness about our "amazing kidneys"Highlight that diabetes and high blood pressure are key risk factors for Chronic Kidney Disease (CKD).

·         Encourage systematic screening of all patients with diabetes and hypertension for CKD.

·         Encourage preventive behaviours.

·         Educate all medical professionals about their key role in detecting and reducing the risk of CKD, particularly in high risk populations.

·         Stress the important role of local and national health authorities in controlling the CKD epidemic. Health authorities worldwide will have to deal with high and escalating costs if no action is taken to treat the growing number of people with CKD. On World Kidney Day all governments are encouraged to take action and invest in further kidney screening.

·         Encourage Transplantation as a best-outcome option for kidney failure, and the act of organ donation as a life-saving initiative.

If detected early, Chronic Kidney Diseases can be treated--thereby reducing other complications and dramatically reduce the growing burden of deaths and disability from chronic renal and cardiovascular disease worldwide!