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Experts say thiazide diuretic blood pressure medications can alter the way your skin reacts to sunlight and increase skin cancer risk in people over age 66.
“Hydrochlorothiazide, one of the most prescribed thiazide diuretic drugs, seems to be the most “phototoxic,” said Dr. Aaron Drucker, a member of the study team as well as a dermatologist and clinical investigator in the department of dermatology at Brown University’s Alpert Medical School in Rhode Island.”
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Diuretics
A- kaliuretic diuretics: 1- Loop diuretics:
* Molecules: furosemide; bumetanide
* Action Site: large segment of the ascending limb of the loop of Henle.
* Action: It inhibits the reabsorption of NaCl (25 to 30% of the filtered sodium)
NB -> this action persists in renal failure
2- Thiazides Related:
* Molecules: hydrochlorothiazide; indapamide (Fludex®)
* Target: the initial portion of the distal…
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