Hematological and biochemical studies were conducted in the Guba-Khachmaz economic region on sheep infected with endoparasites (Babesia ovis–Moniezia expansa) mono- and associatively. For this purpose, blood samples from 45 sick and 10 healthy sheep were examined. Serological and biochemical studies were conducted on sheep infected with a monoinvasion of the primary blood parasite Babesia ovis. Studies were also conducted on sheep infected with an associative invasion of Babesia ovis+Moniezia expansa. For comparison, serological studies were conducted on healthy sheep. The average difference in hematological blood values in sheep with Babesia ovis monoinvasion was as follows: PCV, RBC, MCV, Hb, neutrophils, and monocytes decreased, while WBC, MCH, MCHC, and lymphocytes were relatively elevated. The average difference in hematological values in healthy and sick sheep with monoinvasion did not differ significantly for RBC, MCV, monocytes, WBC, MCH, MCHC, and lymphocytes (p>0.05). In sick sheep with associative invasion of B. ovis+M. expansa parasites, PCV, RBC, WBC, MCV, Hb, monocytes, neutrophils, and lymphocytes decreased sharply, while MCH, MCHC, and eosinophils increased sharply (p0.05). In sheep with associated B. ovis+M. expansa infection, the mean difference in ALT and AST levels was significantly increased, while albumin and total protein levels were significantly decreased (p0.05).
