John Lennon | Β© Robert Whitaker
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John Lennon | Β© Robert Whitaker

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John Lennon, Paul McCartney on train to Essen during German tour leg (1966) Photographer: Robert Whitaker
you're so obvious, kid, but we get it
NEVER SEEN BEFORE photo of John Lennon, photographed by Robert Whitaker, taken during the filming of the music video for "Paperback Writter" on May 20, 1966.
Β©
The Beatles, por Robert Whitaker

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Eric Clapton and Charlotte Martin, a French model active in the late 1960s and early 1970s who was Eric's girlfriend (1965β1968) and later of Jimmy Page (1970β1983) with whom she had a daughter, the photographer Scarlett Page. Photo taken by Robert Whitaker in London, UK, summer of 1967.
There is no good evidence that antipsychotics provide a benefit to first-episode or early-episode psychotic patients.
In short, there is no good evidence that antipsychotics provide a benefit to first-episode or early-episode psychotic patients. Furthermore, the limited evidence that does exist on this question, as reviewed above, suggests that 40% to 67% of such patients could recover without exposure to the drugs, and that this group would, by far, have the best long-term outcomes.
So yes, it is heartening to see the drug-tapering studies. But what is also needed, and needed badly, are studies that assess long-term outcomes with selective-use models of care that avoid immediate use of antipsychotics. This Dutch study reinforces that need, for it does raise a question of whether a first year of treatment with antipsychotics, even at a moderate dose, induces iatrogenic changes in the brain that persist and take a long-term toll.