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Retrosynthesis - Lecture 1 - Benzocaine
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How would you microwave synthesise aspirin?
First step is to do a quick retro-synthetic analysis to see if there are any easy reactions and starting materials we can use:
From this you can search for reactions using these starting materials - I found one in the ACS Journal of Chemical Education (J. Chem. Educ., 2006, 83 (4), p 628) in which they use microwave heating and performed a small catalyst screening. Using a CaCO3 catalyst, the following reaction may be conducted:
Tada!
This is my third quarter of organic chemistry and neither of my professors stressed "blind" retrosynthesis by recognizing patterns in large molecules and suddenly here I am tryna synthesize warfarin BUT I did this to myself and I love it
Song of the day: Feels Like We Only Go Backwards by Tame Impala
Society of Chemical Industry Retrosynthesis challenge.
This looks fun. Ugh why can't Australia do this. May try this as well. CHEMISTS, GO!
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