One of my favorite things about FR is that Ed Greenwood is a trans ally who often answers people's lore questions, and so gender transition does not only canonically exist, but has multiple canonical methods and is accepted by basically everybody. Except maybe drow, who hate everything.

But on the other hand you still have very hierarchical (mostly matriarchal?) systems of gender in parts of the setting. Like Rashemen, where the study of magic is segregated between the the all-female, badass witches of the Wychlaran and the lamer all-male Vremyonni. They both provide different magical services for the country and are never allowed to share their methods with each other or with outsiders, since Rashemen is constantly being menaced and spied on by the undead wizard dictatorship next door who have a thing for infiltrating their organizations and assassinating people. The Wychlaran aren't allowed to show their faces, and the Vremyonni aren't even allowed to leave their seclusion. If you're a magic-user in Rashemen you basically have to join one of the two.