The Phase 1 trial shows the new method could be a very viable option for preventing HIV transmission.
Pre-exposure prophylaxis (PrEP) has been a beneficial fight against the spread of HIV. What started with the pills Truvada and Descovy transitioned into a PreP ring and a recent long-acting injectable to help people avoid the day-to-day doses. Outside of the medically prescribed daily dose of PrEP, however, some people take the PrEP pills only before and after sex instead of all the time, and the Centers for Disease Control and Prevention (CDC) has noted that some off-label, “on-demand” PrEP is protective for men having anal sex with no condom. With all that in mind, a group of researchers under the Contraceptive Research and Development (CONRAD) program are studying whether a quick-dissolving pill inserted into the rectum or vagina would be an effective form of on-demand PrEP. According to Managed Healthcare Executive, the experimental rectal pill contains 20 milligrams of tenofovir alafenamide (Descovy) and 16 milligrams of elvitegravir. -“In nonhuman primates, the insert provided protection from infection when used in the vagina and the rectum,” said Sharon A. Riddler, M.D., professor of infectious diseases at the University of Pittsburg School of Medicine.
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It should be far less expensive if you're not using it daily, not to mention less chance of side effects.












