Dec 23, 2019
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How to prevent keto constipation on the ketogenic diet. Covering magnesium citrate, Inulin and oligofructose prebiotics while on Keto.
Adding prebiotics like inulin and oligofructose while on keto can prevent constipation.
Obesity-Related Gut Bacteria Could be the Real Culprits in “Wear and Tear” Arthritis
Arthritis and joint pain are common afflictions in the obese. However, new research suggests that this may not be due to stressed joints, as widely believed. Instead, the real cause may be body-wide inflammation triggered by the bad gut bacteria that thrive in obese people.
Osteoarthritis is a common side effect of obesity and the greatest cause of disability in the US – affecting 31 million people. Often called “wear and tear” arthritis, osteoarthritis in obese people has long been thought to be a consequence of undue stress on the joints.
However, researchers at the University of Rochester Medical Center have found evidence that the gut microbiome (which is heavily influenced by diet) may be the driving force behind this type of osteoarthritis.
The researchers fed mice a high-fat diet much like a Western “cheeseburger and milkshake” diet. After 12 weeks on the high-fat diet, the mice became obese and diabetic. Their body fat percentage nearly doubled compared to control mice, which were fed a low-fat, healthy diet. The colons of the obese mice were dominated by proinflammatory bacteria, and almost completely lacked beneficial probiotic bacteria (such as Bifidobacteria).
The scientists monitored the gut microbiomes of the mice. They found that changes in the gut microbiomes coincided with signs of body-wide inflammation, including in their knees.
The researchers induced osteoarthritis in the knees of the mice by mimicking a common sports injury (known as a meniscal tear). Interestingly, the osteoarthritis progressed much more quickly in the obese mice than the healthy mice, with almost all of their cartilage disappearing within 12 weeks of the tear.
Remarkably, the effects of obesity on gut bacteria, inflammation, and osteoarthritis were completely stopped when the high-fat diet of the obese mice was supplemented with a common prebiotic, called oligofructose (inulin). The knee cartilage of the obese mice receiving the oligofructose supplement was indistinguishable from that of the lean mice.
The growth of good bacteria, such as Bifidobacteria, was boosted by the prebiotic. In turn, the good bacteria took over and crowded out the bad bacteria. Consequently, the body-wide inflammation was reduced, which slowed the loss of cartilage from the injured knees.
The oligofructose even made the obese mice less diabetic!
There was, however, one thing the supplement didn’t change: body weight.
Obese mice given oligofructose remained obese. Thus, bearing the same load on their joints, yet their joints were healthier!
Simply reducing inflammation was enough to protect joint cartilage from degeneration, supporting the idea that inflammation, not “wear and tear,” drives osteoarthritis and joint degeneration.
Unfortunately, we don’t yet know if the same bacteria that protect the mice from obesity-related osteoarthritis are the same in humans.
The researchers are now planning to move their study to humans.
Reference
Eric M. et al. Targeting the gut microbiome to treat the osteoarthritis of obesity. JCI Insight, 2018; 3 (8) DOI: 10.1172/jci.insight.95997
l'Ami Ricoré n'est plus mon ami, il nous trompe depuis 2007 !
Lassée de ne plus apprécier ma RICORE comme avant, j'ai regardé la boite de Ricoré intense, et comparé les contenus, mais stuppeur, les deux formules ne correspondent plus à la recette de base appliquée depuis 45 ans au moins,
OligoFructose Shows Promise for Weight Management
OligoFructose Shows Promise for Weight Management
A study out of a Canada published in Obesityjournal found that oligofructose (aka fructooligosaccharide), a prebiotic fiber commonly found in food sources like chicory, onion and oat, may aid in weight management. The researchers put two groups of rats on a strict high-fat, high-sugar diet, but one faction was also fed oligofructose, and guess what? Even though both rat packs were chowing down…
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What signs give the best advice? Personally, I always find myself asking either my taurus, virgo or libra friends for advice, but is there a general rule? PS Thank you for updating this blog so regularly, it really is one of my favorites on tumblr :)
Thank you very much :D
Taurus, Virgo, and Libra are wonderful examples of signs with the best advice. Joan, who also runs this blog is a Virgo, and she is always the one I go to if I need help. Cancer would definitely make it on that list, and Scorpio or Capricorn if you catch them on the right day, and in the right mood!
-Peyton