#mice model

The global Mice Model (Models, services and care products) market is expected to grow at a CAGR of 7.2% during the projected period to reach USD 1,370.54 million by 2023 from USD 968.36 million in 2018. The growth of this market is mainly attributed to the continuing modification in mice model for cancers, immune diseases, and rare diseases; increasing devouring of personalized medicine propelling the demand for humanized mice model; rising grants and investments for biological research; rising pharmaceutical R&D activities; and increasing focus of International Mouse Phenotyping Consortium (IMPC) and International Knockout Mouse Consortium (IKMC) on the development of embryonic stem cells as well as knockout and mutant mice.

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The evolution of alternative techniques to animal testing, improvement in zebrafish model development, and growing need for improved mice models are the major challenges in the global mice model market. In addition, evolution of CRISPR-Cas9 gene editing technology in the field of biomedical research, increasing demand for humanized mice model, and rising monoclonal antibody production provides significant opportunities for the various stakeholders in the global mice model market. However, factors such as increasing use of rat models, increased advantages from cryopreservation, and government regulations and laws for ethical use of animals in research hampers the growth of mice model market to some extent.

Market dynamics:

The continuous modification in mice model allows researchers to find out the appropriate solution for complex biology during the treatment of various chronic diseases. The mouse models are playing important role in the development of immune therapies. For instance, the recent research led by University of California developed a new class of drugs known as immune checkpoint inhibitors. These drugs have been used for the treatment of a growing number of patients with cancer, including some who had run out of treatment options.

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Cancer remains to be the second leading cause of death in the U.S., it was estimated that in 2017, 30% of all new cancer cases among women were breast cancer. In 2018, the federal budget prioritizes Medical Research and Cancer Prevention, which includes a $3 billion increase for medical research at the National Institutes of Health (NIH) a $275 million increase for the National Cancer Institute (NCI); a $10 million increase for cancer prevention programs at the Centers for Disease Control and Prevention (CDC).

trends

The rapidly growing ageing population and advances in cancer therapy have sparked tremendous interest in the improvement of mice models. For many years, cancer biologists have taken two distinct approaches to modeling cancer. One is to grow immortalized human cancer cells, known as cancer cell lines in a lab dish, but they don’t really reproduce the complex in vivo environment of a tumor.

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Mice Model Market Worth 1,370.5 Million USD By 2023

According to this latest publication from Meticulous Research®, the global mice model market is poised to grow at a CAGR of 7.2% from 2018 to 2023 to reach USD 1,370.5 million by 2023, driven by continuing modification in mice model for cancers, immune diseases, and rare diseases; increasing devouring of personalized medicine propelling the demand for humanized mice model; rising grants and investments for biological research; rising pharmaceutical R&D activities; and increasing focus of the International Mouse Phenotyping Consortium (IMPC) and International Knockout Mouse Consortium (IKMC) on the development of embryonic stem cells as well as knockout and mutant mice. Moreover, evolution of CRISPR-Cas9 gene editing technology in the field of biomedical research, increasing demand for humanized mice model, and rising monoclonal antibody production provides significant opportunities in this market. However, increasing use of rat models, increased advantage from cryopreservation, and stringent government regulations and laws for ethical use of animals in research hinders the growth of mice model market to some extent.

Meticulous Research® –leading global market research company published a research report titled “Mice Model Market by Type (Inbred Mice, Outbred Mice, Genetically Engineered Mice), Service (Breeding, Rederivation), Therapeutic Area (Oncology, Heart Disease), Technology (CRISPR Cas9, SCNT), Mice Care Product (Cage, Feed), and End User- Global Forecast to 2023”.

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The global mice model market study presents historical market data in terms of value (2016 and 2017), estimated current data (2018) and forecasts for 2023- by type (inbred mice, outbred mice, genetically engineered mice, hybrid mice, immunodeficient mice, and spontaneous mutant), service (breeding, cryopreservation & cryorecovery, quarantine, rederivation,  model in licensing, genetic testing, and other services), therapeutic area (oncology, immunology & inflammation, cardiovascular, diabetes,  neurobiology, rare diseases, and other diseases), technology (CRISPR-Cas9, embryonic stem cell injection, microinjection, somatic cell nuclear transfer, other technologies), mice care products (cages, feed, bedding, others), and end user (academic and research institutes, pharmaceutical and biotechnology companies, contract research organizations, and others). The study also evaluates industry competitors and analyzes the market at regional and country level.

The inbred mice models are being widely adopted for huge preclinical trials during drug discovery process. These models held the largest share in 2017; however, genetically engineered mice models are set to be the emerging and rapidly growing type of mice model.

Services form an essential part of the mice model market and breeding services comprised the major share in 2017. This segment is expected to witness the fastest growth mainly attributed to their ability to produce adequate quantity of desired litters which help researchers to conduct various preclinical trials during drug discovery process.

This research report analyzes major geographies and provides comprehensive analysis of North America (U.S. and Canada), Europe (Germany, U.K., France, Italy, Spain, and RoE), Asia-Pacific (Japan,China, India, and RoAPAC), Latin America, and the Middle East & Africa. North America accounted for the major share in the global mice model market in 2017, followed by Europe, and Asia-Pacific. The major share of the North American region is mainly attributed to the presence of established pharmaceutical & biotechnology industry and advanced biomedical research field showing huge demand for mice model for the drug discovery process, increasing R&D expenditure, and various government initiatives. However, Asia-Pacific region possesses lucrative growth potential for the mice model market during the forecast period. This is mainly attributed to the increasing growth in government & private sector, growing biomedical & personalized research areas, and rising focus on the regenerative medicine in order to understand the translational research field.

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The key players in the global mice model market are Charles River Laboratories International, Inc. (U.S.), The Jackson Laboratory (U.S.), Laboratory Corporation of America Holdings (U.S.), Horizon Discovery Group plc (U.K.), Trans Genic Inc. (Japan), genOway (France), Taconic Biosciences, Inc. (U.S.), Envigo (U.S.), JANVIER LABS (France), Ingenious Targeting Laboratory (U.S.), and Harbour Antibodies BV (The Netherlands).

Key questions answered in the report-

Which are the high growth market segments in terms of mice model type, service, therapeutic area, technology, end user, mice care products, and regions/countries?

What is the historical market for mice model across the globe?

What are the market forecasts and estimates from the period 2018-2023?

What are the major drivers, restrains, opportunities, and challenges in the global mice model market?

Who are the major players in the global mice model market and what share of the market do they hold?

Who are the major players in various countries and what share of the market do they hold?

What are the competitive landscapes and who are the market leaders by sub-region in the global mice model market?

What are the recent developments in the global mice model market?

What are the different strategies adopted by the major players in the global mice model market?

What are the geographical trends and high growth regions/countries?

What are the local emerging players in the global mice model market and how do they compete with the global players?

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Perfected the years, this market, which includes models and services, has witnessed many innovations that have led to an increase in the application areas. For instance, mice models are widely used in preclinical research in a number respecting academic institutions all around the world and also in favor various industries including pharmaceutical, biotechnology, biopharmaceutical, orthodontic research, biomedical substantiate, and others.<\p>

The unintermitting growth of this market is attributed to their ability in contemplation of reproduce the same results inpouring different laboratories over a period of innings. However, the knockout mice model market is the fastest-growing market due for the exalt corridor the number of investments in the development anent knockout mice models. One as regards the eldest investments includes $110 million by the National Institutes in reference to Robustness (NIH) (U.S.) for a resonance frequency of nine years to initiate the second phase of the Knockout Fingerling Project (KOMP2) in September 2011. In the mice prototypal services rural market, the fission market is expected to originate at the highest CAGR. This is indebtedness till the increase in the display re mice as well as the increase swish use referring to mice by companies, which has inflated the need to manage the breeding of these mice in an effective manner. Exempli gratia, the growing market for mice models is likely into boost the market for breeding services.<\p>

In the coming years, the growth of the mice model market is fitted to be focused on Tile, India, Japan, Brazil, and Mexico. These countries offer a wide regimentation of opportunities for growth and are tenable to serve as net pockets in preference to the mice model unsteady market. Stick these countries offer high-growth potential parce que compared to compose markets ally as the U.S. and U.K.<\p>

Report Description

Mouse is a popular model system because it is a mammal with sophisticated genetic tools and significant genetic resources. The prospect of the mice as a model for exploring human pathophysiology and disease progression and for developing drugs is likely to be further widened by the introduction of new models such as immunedeficient and humanizing mouse in which human tissues and cells or genes are reconstituted. With 99% of their genes shared with humans, new possibilities were opened for genetic testing. Furthermore, the conservation of genetic association within the mice and human genomes with respect to the encoded genes and their alignment along chromosomes has been a great advantage in the identification of potentially conforming homologous mutations and disease genes.

This report studies the global mice model market from five perspectives: by type of model, application, services, and geography. Based on type of model, the market has been segmented into hybrid/congenic, transplantation mouse, transgenic, knockout, carcinogen-induced and spontaneous mouse, outbred, inbred, and conditioned/surgically modified. Based on application, the market has been segmented into immunology, central nervous system, oncology, cardiovascular, diabetes, and metabolism & regulation. Some of the prominent services offered to end-users include breeding and rederivation, cryopreservation and cryorecovery, quarantine services, genetic testing, model in-licensing, in vivo and in vitro pharmacology services, genetically engineered model services and other services such as surgical and line rescue.

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Scope

The global mice model market was valued at USD 1,008.1 million in 2014 and is projected to reach USD 1,749.3 million in 2023, expanding at a CAGR of 6.4% from 2015 to 2023. Asia Pacific is expected to be the fastest growing market for mice model during the forecast period from 2015 to 2023. This high growth is primarily due to improving economic condition in countries such as India and China, and increasing number of academic and research, and contract research organizations in Asia Pacific. Japan, China, Australia, and India are the major markets in Asia Pacific that offer immense opportunities to companies in the mice model market

Key Players

Key players operating in the global mice model market include Charles River Laboratories, Crescendo Biologics Limited, Deltagen, Inc., genOway S.A., Harlan Laboratories, Inc., ImmunoGenes AG, Taconic Biosciences, Inc., Lexicon Pharmaceuticals, SAGE Labs, The Jackson Laboratory, and TransGenic, Inc.

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