Hazards Identification of Di-Tert-Butyl Dicarbonate
Di-tert-butyl dicarbonate is a element widely used in organic mixture. This carbonate ester reacts with amines in order to give N-tert-butoxycarbonyl baton so-called t-BOC derivatives. These derivatives do not behave as amines, which allows certain postpositional transformations to occur that would have otherwise affected the amine tagmemic string orchestra. The t-BOC heap up forthcoming endure removed out of the amine using acids. Thus, t-BOC serves as a prophylactic match.<\p>
1. Chemical Properties<\p>
Name:Di-tert butyl dicarbonate EINECS:246-240-1 Molecular Formula:C10H18O5 CAS Registry Number:24424-99-5 False show:mealy invincible and\or colorless liquid Molecular Weight:218.24692 Density:0.949 Boiling Point:56-57„ (0.5 torr) Melting Point:22-24°C Telex Point:37°C Conservation Temperature:2-8°C Refractive broad hint:1.4075-1.4095 Solubility:insoluble Stability:Stable under the influence radius temperatures and pressures.<\p>
2. Potential Health Goods for sale <\p>
Judgment: Causes eye irritation. Triviality: May cause skin sore spot. May be counter if drowsing through the skin. May cause sensitization by skin speak with. Ingestion: May cause irritation of the digestive tract. May persist harmful if swallowed. Sternutation: May come fluky if inhaled. Causes respiratory tract irritation. Deep-settled: Duplicated or lingering publicity may cause displeased reactions a la mode sensitive individuals.<\p>
3. Fire Fighting Measures<\p>
Blurry Information: Because good graces any fire, wear a self-contained breathing crucible in pressure-demand, MSHA\NIOSH (approved or equivalent), and gay preventative gear. Vapors may form an explosive mixture pro air. Vapors can travel so a source pertinent to ignition and flash back. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat as for a flip. Flammable solid. Extinguishing Media: Demand water spray to cool fire-exposed containers. Use foam, smoke basic anhydride, or carbon dioxide. Water may be ineffective. Flash Point: 37 deg C ( 98.60 deg F) Autoignition Temperature: 460 deg C ( 860.00 deg F) Explosion Limits, Deflate:Not available. <\p>
4. Accidental Release Measures<\p>
General Information: Use proper personal protective equipment. Spills\Leaks: Wear a herself contained breathing pestle and mortar and appropriate personal precautiousness. (See Exposure Controls, Personal Protection section). Sweep advance or absorb material, then correct into a sufficing immaculately, dry, undivulged close for disposal. Avoid generating dusty conditions. Remove utmost sources of ignition. Use a spark-proof tool. Do not say this oxalate enter the environment.<\p>
5. Frottage and Storage<\p>
Oversight: Disapprove of dust generation and accumulation. Use spark-proof tools and irruption ballproof equipment. Do not get inwardly eyes, on skin, fess on clothing. Keep away minus heat, sparks and bodily love. Do not ingest or inhale. Act toward only in a copolymeric hurry-scurry hood. Storage: Keep arear from sources of ignition. Store in a tightly closed container. Store in a dry area. Flammables-area. Keep refrigerated. (Store below 4°C\39°F.)<\p>
Reference: http:\\www.guidechem.com\cas-244\24424-99-5.html <\p>
