#intracellular

Many biologically compelling proteins are deprioritized because they cannot be easily assayed in cells, creating a disconnect between biochemical discovery and physiological relevance. Debuted at the Society for Laboratory Automation and Screening (SLAS) International Conference and Exhibition on February 10, 2026, Promega’s TarSeer™ BRETSA™ Target Engagement System seeks to bridge that divide.…

Science, Volume 389, Issue 6755, Page 48-52, July 2025. Summary Without knowing the specific article in the mentioned Science issue, I can only provide a general summary. Science journal typically publishes cutting-edge research across a wide range of scientific disciplines. Volume 389, Issue 6755, pages 48-52, likely contains a single peer-reviewed research article or a short report, potentially…

Intracellular Pathogens

This short video animation explains about how bacteria enter healthy cells and cause infection by multiplying and penetrating other healthy cells through macrophage generation. It also describes how the pathogens move through the circulatory system and spread infection through the body.

Evidence of protein folding at site of intracellular droplets — ScienceDaily

Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells — like drops of oil in water. In a study published in the journal Chemical Science, researchers at the University of Notre Dame found that elevated concentrations of proteins within the droplets triggered…

Tumor cells attacked from intracellular region

Fig.1: The efficacy of 211At-AAMT using the PANC-1 xenograft model. Tumor growth inhibition by 211At-AAMT (left). Coronal images of 211At-AAMT in tumor-bearing model (right). Credit: Osaka University A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues. Inhibiting the function of LAT1 has been known to have anti-tumor effects, but there has been limited…