#ibrutinib

In my last post, I talked about what lead me to here. Treatment. Let’s step back a bit and think back to how my treatment options came about.

My husband and I had been living our lives in Sydney. We both had secure jobs, a nice place to live in a great area and started our fur baby family with two beautiful cats. Although it seemed like we were “living the dream”, we both felt something was missing. We just weren’t happy living and working in the city. We tried to balance this by moving into a semi rural area though this just didnt cut it. We often have conversations about what our dreams and long term goals are. We both came to the realisation - what are we waiting for? Why do we continue to live in the auto-pilot lifestyle that is clearly not making us happy? 

In early October, we flew to Canada to commit our lives, love and souls to each other with the thought that “we’ll see how we feel when we come home”. We returned to Australia 3 weeks later, returned to work a week after and told our boss that we’re moving to Adelaide. 3 months later we moved.

As most people do, “Why Adelaide?! There’s nothing there!”. For us, it has everything we need and want for our dreams and long term goals. Family, affordable blocks of land to build our dream home and beautiful land and beaches. Not to mention loads of farmers markets - my favourite pass time. 

The move it self was a fairly easy decision for us though it didn’t come without its fear of the unknowns. Will we still have secure jobs? What will my new specialist be like? Will there be a GP I’ll click with and understand my condition? All of the above on top of just packing and moving caused a fair bit of anxiety. Luckily, we had a place to move to, our employer said we still have jobs and we all arrived in 1 piece. 

Before we even moved, I had an appointment to meet my Adelaide specialist. We clicked straight away. She’s personable and very switched on. At my second appointment, she mentioned that the hospital is going through the process of becoming an “active site” to hold a clinical trial for CLL. She said that she feels its the best option for treatment for me. This replicated what my Sydney specialist had been saying to me since I was diagnosed - “we keep an eye out for clinical trials - its the best treatment option available”. Over the 3 years, since I was diagnosed, no clinical trials came up that I was able to apply for. Often they are for people who have already gone through treatment and the CLL had came back or relapsed or I would purely be discounted on age. Yet within 2 months of moving to Adelaide, there’s a clinical trial that I can apply for. This is where I say - the move to Adelaide was the right move and must have been fate. 

Although I am starting this blog 2 weeks into my treatment for CLL, I feel it’s important to take a look back where it all began and what my family, friends and of course myself have been through over the the year. I often get asked about how I got diagnosed. What signs were there. To be honest, I got lucky. Some people don’t get diagnosed this early as most symptoms can be shrugged off to be related to something else as they can be very mild.

My journey on the CLL road began in August 2013. I had noticed a painful bump about the size of a pea at the base of my skull. If it were on any other place in my body, it probably would have gone unnoticed though this was sitting right at the base of skull which made laying down to sleep painful. Although I thought it was a bit out of the ordinary, I didn’t pay much attention until I came down with a virus which knocked me for 6. I was unwell for about a week so I decided to go to the GP for a check up. 

I hadn’t really had to find a “go-to” GP as yet, as we had just moved into a new area, so I just went to the local medical centre and they booked me with the first available doctor. 

I sat down and explained to him how I had been feeling - lack of energy, this painful bump at the base of my skull and overall just not feeling well. He first suggested that I had a virus (he was right) and to let it run its course. If I didn’t feel better in a few days to come back. I didn’t so I did. He’s now suggested to run some blood tests basically to eliminate anything he can think of. 

I’ve never had so many viles of blood taken in one go in my life. I’m not the best at having blood taken (well I wasn’t then - now I’ve had to get used to it!). I was still not feeling well, I hadn’t eaten, I was feeling dehydrated so yes - half way through I passed out and threw up. I was kind enough to forewarn the blood lady before I passed out - thankfully because for some reason the only chair they had in this room was a bar stool essentially - who ever thought that was a good idea for blood taking?! Anyway, so I wake up now laying on the bed they had there and the lady says to be “I’m sorry - but I didn’t get all the blood I needed”. I just wanted it all to be over after all on top of not feeling well, I just embarrassed myself in front of a total stranger. Anyway, she got the job done and I walked out with my husband who had been sitting in the waiting room completely unaware of what had just happened...

I got a call the next day asking for me to go in and see the doctor - This is never a good sign. I went in and sat down. From here on out is a bit of a blur. All I remember is the doctor telling me that he believes I have CLL and that he is giving me a referral to a haematologist for further testing. The only other thing I remember from the visits seeing him during the investigations was the doctor explaining to me that his brother has CLL and how he has gone through treatment and living a perfectly normal life. At the time, this didn’t help the shock and fear around being told that I had cancer. Now when I look back, I think fate was working in my favour that day when I was booked with that particular GP. 

Over the week following, I was at the hospital multiple times - waiting to see the haemotologist, getting a CT scan, getting a bone marrow biopsy...

After all this, in September 2013, at the age of 31, I was diagnosed with Chronic Lymphocytic Leukemia also known as CLL. For those of you relatively new to understanding CLL, the fact I was even diagnosed with CLL is quite rare. The Leukemia Foundation states that over 80% of the people diagnosed are over 60 and that CLL is rare in people under 40. It is also more common in men than in women. I am the youngest person that my specialists have treated. So when I start asking questions about fertility and the chance of passing CLL to my potential children - I did get a lot of “I’m not sure - I’ll need to do some research”.

Ibruxen 140 mg, also known by its generic name Ibrutinib, is a medicine used for the treatment of certain types of blood cancers. It belongs to a group of medicines called Bruton’s tyrosine kinase (BTK) inhibitors. By blocking this enzyme, the medicine helps stop cancer cells from growing and spreading in the body. Doctors prescribe Ibruxen 140 mg mainly for conditions such as chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and Waldenström’s macroglobulinemia (WM).

What is Ibruxen 140 mg?

Ibruxen 140 mg is an oral capsule taken by mouth. It works by targeting and blocking a protein that cancer cells need to survive. Unlike traditional chemotherapy, which affects both healthy and cancer cells, Ibruxen focuses more on cancer cells. This makes it an important treatment choice for patients who may not tolerate strong chemotherapy.

Medical Uses of Ibruxen 140 mg

Doctors prescribe Ibruxen 140 mg for:

Chronic Lymphocytic Leukemia (CLL): A slow-growing blood cancer that affects white blood cells.

Mantle Cell Lymphoma (MCL): A rare type of non-Hodgkin’s lymphoma.

Waldenström’s Macroglobulinemia (WM): A rare type of lymphoma that causes excess protein in the blood.

Other cancers: In some cases, doctors may use it for other conditions depending on the patient’s needs.

How to Take Ibruxen 140 mg

Ibruxen 140 mg should be taken once daily with a glass of water. It is usually swallowed whole and should not be crushed or chewed. The dosage depends on the type of cancer and the patient’s health condition. Always follow the doctor’s advice for best results.

Benefits of Ibruxen 140 mg

Helps slow down or stop the growth of cancer cells.

Improves survival rates in patients with blood cancers.

Offers a targeted treatment with fewer side effects compared to chemotherapy.

Can be used as a long-term treatment to manage cancer.

Possible Side Effects

Like all medicines, Ibruxen 140 mg may cause side effects. Common side effects include:

Diarrhea

Tiredness

Nausea

Muscle and joint pain

Low blood counts

Serious side effects are rare but may include bleeding problems, infections, or irregular heartbeat. Patients should report any unusual symptoms to their doctor immediately.

Safety Precautions

Take the medicine only as prescribed by your doctor.

Avoid grapefruit and Seville oranges as they can affect how the medicine works.

Inform your doctor about other medicines you are taking.

Regular blood tests may be required to monitor health during treatment.

Conclusion

Ibruxen 140 mg contains Ibrutinib, a targeted therapy used to treat certain cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.

#Ibruxen #140mg #Ibrutinib #Medicine #OnlineMedicine #Health

Ibrutinib is a recently discovered drug for B-cell cancer, which is marketed by major pharmaceutical companies. It comes under the brand name Imbruvica & active ingredient is Ibrutinib. The Cost of Ibrutinib is different in every other country, however, you can definitely find some discounts if you buy it online rather than at a drug store. It is known that Ibrutinib price is approximately 4$ Per pill per 30 Capsule of 140 mg in India. The Indian drugmaker has cut-price versions of this cancer drug.

However, the Ibrutinib price varies from country to country, the cheapest price is expected to be in India due to the production of the medicine here itself in Hyderabad. Now You can buy Ibrutinib online at the lowest price in India which is available in the brand name as Ibrunat 140 mg, Nitib. That cost is quite very affordable available with us for 30 Capsules of Ibrutinib 140 mg. For more information about buying and pricing please contact us.

  Ibrutinib, primo inibitore della tirosin chinasi di Bruton (BTK) ad essere stato approvato a livello mondiale e sviluppato da Johnson & Johnson, ha recentemente ricevuto dall’agenzia italiana del farmaco, AIFA, la rimborsabilità per una nuova indicazione terapeutica. In particolare, il farmaco è ora disponibile anche in combinazione con venetoclax, inibitore di BCL-2, come nuovo trattamento per…

Ibrunat 140mg is a medication containing the active salt Ibrutinib, designed to treat various B-cell cancers, such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Ibrutinib works by inhibiting specific enzymes that promote cancer cell growth.

Janssen, azienda farmaceutica del gruppo Johnson & Johnson, ha presentato al Congresso annuale dell’American Society of Hematology (ASH) i nuovi dati a lungo termine dello studio di fase 3 GLOW e dello studio di fase 2 CAPTIVATE, entrambi volti a valutare l’efficacia del trattamento a durata fissa della combinazione ibrutinib più venetoclax (I+V) in prima linea. Ad un follow-up di 57 mesi, lo…