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Maud Menten was born on March 20, 1879. A Canadian bio-medical and medical researcher who made significant contributions to enzyme kinetics (the study of the rates of enzyme-catalysed chemical reactions) and histochemistry (the process of selectively identifying antigens/proteins in cells). She is primarily known for her work with Leonor Michaelis on enzyme kinetics in 1913.
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Pharmacognostical standardisation of an epiphytic orchid, Luisia tenuifolia Blume.
Pharmacognostical standardisation of an epiphytic orchid, Luisia tenuifolia Blume. https://jppres.com/jppres/pdf/vol10/jppres21.1159_10.1.113.pdf #Pharmacy #Pharmacology #Pharmacognosy #NaturalProducts #TraditionalMedicine
Image: Naturalist Ecuador Article published in the Journalof Pharmacy & Pharmacognosy Research 10(1): 113-127, 2022. Sakthi P. Sethuraman, Kumar P. Ramachandran* Department of Pharmacognosy, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai TN,…
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HISTOLOGICAL, HISTOCHEMICAL AND SCANNING ELECTRON MICROSCOPIC STUDIES ON INTESTINE OF FRESHWATER CATFISH Horabagrus brachysoma (GUNTHER, 1864), EMPHASIZING ON GUT-ASSOCIATED LYMPHOID TISSUE | UTTAR PRADESH JOURNAL OF ZOOLOGY
The current research included histological, mucin histochemical, and surface ultrastructural studies. The sections were stained with haematoxylin and eosin, periodic acid-Schiff, and Alcian blue, as per standard histological procedures. The intestine was examined using a scanning electron microscope (SEM). The research discovered four histological layers in the intestine, which are close to those found in other catfish species. During histochemical experiments, goblet cells staining positive for neutral and acidic mucins were discovered. Broad, irregular wavy folds with microridge pattern of epithelial cells and goblet cells with expelled mucin droplets were found on the mucosal surface of the intestine, according to SEM observations. The aim of the research was to learn more about the catfish's gut associated lymphoid tissue (GALT). GALT was found in the intestine of H. brachysoma, consisting of dispersed populations of cells such as lymphocytes, granular cells, macrophages, and plasma cells, as well as intraepithelial and intralaminal leucocytes (ILLs). In the intestine of the catfish, there was no accumulation or aggregation of lymphoid cells. These immune cells detect GALT and, along with secreted mucus, provide the first line of defence against pathogens in the gut. Please see the link :- https://mbimph.com/index.php/UPJOZ/article/view/1965
You can learn a lot by looking - cool pics from our recent work
You can learn a lot by looking - cool pics from our recent work. Part I - immunohistochemistry of human tissues. Click the link for more. #academicchatter #phdforum #imaging #microscopy #research .
Part I – immunohistochemistry
As a little positive aside from all the COVID-19 related news, here is the first of a collection of cool science pics generated by the team over the last few months. Today’s post features a selection of immunohistochemistry images from human tissues.
Click on the first image to view as a slideshow.
What you are looking at:
Each of these images is a…
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Vascular Endothelial Growth Factor Study of Placenta in Preeclampsia | Chapter 15 | Emerging Research in Medical Sciences Vol. 3
Preeclampsia is defined as new onset hypertension and albuminuria in previously normotensive pregnant women after 20 weeks of pregnancy. There is no cure; management is reliant on a structured antenatal surveillance programme and antihypertensives. Recent advances in immune histochemistry study of placenta have elucidated an increased Vascular Endothelial Growth Factor (VEGF) expression in various placental bed disorders like recurrent pregnancy loss, preeclampsia, fetal growth restriction, preterm and abruption placenta. Increased release of VEGF family proteins has been attributed to atherosis and placental hypoxia. However, some studies have found normal VEGF concentrations in placenta in these disorders of feto-maternal interphase. This chapter aims to analyse the VEGF expression in placental biopsy from preeclampsia and normotensive pregnancies.
VEGF density is more in the placentas from preeclampsia pregnancies as compared to placenta from a normal pregnancy. The mean weight of placenta is smaller in preeclampsia group. Additionally, the fetal capillaries are also small in diameter and lumen was collapsed. The pulsatility index of uterine artery supplying the placenta is also higher in preeclampsia pregnancies. The high velocity blood flow can mechanically damage the tender fetal villi floating in the intervillous space. This damage collapses the fetal capillaries as evidenced by the smaller diameter of fetal capillaries in the placental biopsy.
Placental hypoxia in cases of preeclampsia is a potent stimulus for VEGF expression. Nevertheless, the increased VEGF expression should be seen in the light of collapsed fetal vessels in a small placenta. Author(s) Details
Dr. Jayavelan Ramkumar Department of Cardiothoracic Vascular Surgery, Sri Ramachandra Medical College, Sri Ramachandra University, Chennai, India.
Benjamin M. Sagayaraj [Head of the Department] Department of Pediatrics, Saveetha Medical College, Saveetha University, Chennai-602105, India.
Dr. Nidhi Sharma Department of Obstetrics and Gynaecology, Saveetha Medical College, Saveetha University, Chennai-602105, India.
View Books: http://bp.bookpi.org/index.php/bpi/catalog/book/118
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RNA content in mammalian muscle fibres
RNA content in mammalian muscle fibres
This important research was part of the PhD work carried out by Petra Habets in the research group headed by Professor Anthony J Sargeant. It was a collaboration and jointly supervised by Anton Moorman of the Academic Medical Centre, of the University of Amsterdam. Sadly one of the inspirations for this research and close friend Jose Sant’Ana Pereira died, much too young, a few years after this…
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Regional variation in recruitment and physiological properties of a single muscle
Regional variation in recruitment and physiological properties of a single muscle
This research published in the Journal of Neurophysiology was carried out in Amsterdam by Jo De Ruiter as part of his doctoral thesis supervised by Professor Anthony J Sargeant and Arnold de Haan. It was part of a series of studies examining the regional differences within a single muscle of physiological properties and hence pattern of recruitment in response to different intensities of exercise.
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Muscle Fibre can co-express different isoforms of Myosin Heavy Chain
Muscle Fibre can co-express different isoforms of Myosin Heavy Chain
Anthony Sargeant directed this work on skeletal muscle as Head of the Amsterdam research group. The meticulous work was carried out by Jose Sant’Ana Pereira who was one of Tony Sargeant’s PhD students. The mATPase histochemical profile of rat type IIX fibres: correlation with myosin heavy chain immunolabelling
Jose A A Sant’Ana Pereira, Arnold de Haan, Wessels A, Anton F Moorman, Anthony J…
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