#gdf15

A new study clarifies how a mysterious hormone, GDF15, makes insulin work better in rodents. As reported in Cell Metabolism, the researchers were the first to discover that the hormone GDF15 actually improves sensitivity in mice and rats, making them better suited to regulate their blood sugar and absorb energy in their muscles. The findings increase our general understanding of GDF15 and suggest potential benefits for diabetes and overweight. “Increased insulin sensitivity is an important indicator of health and critical for avoiding type 2 diabetes, high blood pressure, and cardiovascular diseases. That we are now able to demonstrate a beneficial effect of GDF15 in rodents raises interesting perspectives,” says senior author Erik Richter, a professor at the University of Copenhagen.

Un nuovo studio dimostra che topi geneticamente modificati per non essere in grado di produrre l’amminoacido cisteina e alimentati con una dieta priva di cisteina hanno perso il 30% del loro peso corporeo in una sola settimana. Il lavoro dimostra che la deplezione di cisteina interrompe i normali percorsi metabolici utilizzati dalle cellule dei mammiferi per convertire il cibo in energia,…

Biomarker in Glaucoma Damage Identified

Glaucoma, a leading cause of blindness worldwide, most of the time is diagnosed during a typical eye examination. Over time, accelerated stress within the eye damages the optic nerve, leading to vision loss. Unfortunately, there is no solution to properly predict which patients might lose vision quickly. Now, while studying mice, rats and fluid removed from the eyes of sufferers with glaucoma,…