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Shana to Tomoka Minato [Story Mode], Dengeki Bunko: Fighting Climax IGNITION (French Bread/ SEGA) Submitted by @annon-guy2

Shana to Rentaro Satomi [Story Mode], Dengeki Bunko: Fighting Climax IGNITION (French Bread/ SEGA)

Ako, Dengeki Bunko: Fighting Climax: Ignition (French Bread/ SEGA)

Dr. Atkins   Katelyn M. Atkins MD PhD Harvard Radiation Oncology Program Dana-Farber Cancer Institute Brigham and Women’s Hospital Boston, Massachusetts     MedicalResearch.com: What is the background for this study? What are the main findings?  Lung cancer remains the leading cause of cancer-related death worldwide and nearly half of patients will require radiation therapy as part of their care. Cardiac toxicity following radiotherapy has been well-studied in breast cancer and lymphomas, however the impact of cardiac toxicity following lung cancer radiotherapy has historically been under-appreciated due to the high risk of lung cancer death. Recent studies highlighting cardiac toxicity following lung cancer radiotherapy have been limited by small numbers of patients and, to our best knowledge, have not included validated cardiac event endpoints defined by the American Heart Association (AHA)/American College of Cardiology (ACC). MedicalResearch.com: What did you do to solve this problem in oncology?  We aimed to determine whether cardiac radiation dose exposure was associated with an increased risk of Major Adverse Cardiac Events (MACE), as defined by the AHA/ACC, and mortality. We performed this comprehensive analysis using one of the largest cohorts of locally-advanced lung cancer patients.  MedicalResearch.com: What are the main findings?  We found that despite a high competing risk of death from lung cancer, cardiac radiation dose exposure is a modifiable cardiac risk factor for Major Adverse Cardiac Events and mortality. In particular, patients without pre-existing heart disease had a significantly higher risk of Major Adverse Cardiac Events and mortality when they received higher cardiac radiation doses (≥10 Gy) versus lower cardiac radiation doses ( Read the full article

Dana-Farber Cancer Institute main loggy

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