Most cold sterilization solution render instruments sterile only after a 10 hour immersion. This prolonged chemical action can be more detrimental to the surgical instruments than the usual 20 minute autoclave cycle. If the instruments need to be “disinfected” only, cold sterilization is okay as disinfection will place in only 10 minutes. But keep in mind the difference between: STERILE- an absolute term (no living organism survives) and DISINFECTED– basically clean Always use the proper sterilization/ cleaning technique to render the instrument in required condition for use. For instruments with Tungsten Carbide inserts (Needle Holders, Scissors, Tissue Forceps), we do not recommended use of solution containing Benzy| Ammonium Chloride which will destroy the Tungsten Carbide Inserts.