When Hannibal feels the first sharp sting of it, he is, fortunately, alone.
In his study, the fire blazing bright despite the overly-warm weather outside, he shifts his weight, a tendril of warmth that has nothing to do with the fire running from the base of his neck to the small of his back. It dances down his spine, falls and curls like a rope artist in a circus, settles low in his belly. His fingers tremble, and clench around the stem of his wine glass, and he looks up from his book and sets his eyes on the fire.
"…Interesting," he murmurs.
He says it the same way a commander might order to drop a bomb on a city. He sets his glass down, carefully, and waits until the sensation goes away. He curls his fingers up tightly, rests his fists on his thighs, and forces his hands flat against the soft material of his suit pants. They slide down to his knees, then back up, and he breathes out as the feeling fades like a contraction.
The clock on the mantle reads that it's just past ten at night. He has several hours before his natural sleep patterns are due to rear their head, but he feels abruptly drained, and tired, as he has come to expect from his thorough research on the subject. It is, unfortunately, an unavoidable trick of biology, but one he had not expected for several more years.
He pushes himself to his feet, wine forgotten, and goes to his appointment book. He has several patients scheduled over the next few days, and on the next page noting the beginning of the new week, he circles the date and makes a note to keep that week clear.
He will be in no condition to tender and cater to his patients, if he even makes it that far.
He has prepared for this, of course. No self-respecting Omega of his stature and skill would deign to let themselves be taken by surprise. Although, again, he has not expected his final heat to approach for some time, it is one of those occurrences people prepare for like Doomsday. He has plans, and bags packed, and knows what he will need to do, to make sure he makes it through the ordeal with minimal discomfort.
The first step will be to hunt, to stock his fridge and his stores so he will not go hungry.
The second step will be to find a suitable companion.