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Determination of the Stress-Index After Long Walking and 4 Cups of Instant Coffee in Adult Man Biomedical Journal of Scientific & Technical Research

https://biomedres.us/fulltexts/BJSTR.MS.ID.005824.php

It is known that coffee and its caffeine have an invigorating and stimulating effect on the human body. The mechanism of action is carried out by activating the sympathetic nervous system and increasing stress hormones. We measured the level of stress and other parameters of Pulse Rate Variability (PRV) in a 60-year-old man [1,2]. He is 178 cm tall, weighs 75 kg and has a BMI of 24. In our case, we measured the Stress-Index and other parameters of Heart Rate Variability (HRV) for 1 minute 30 seconds using a chest belt with Heart Rate Monitor “Kalenji” (with Bluetooth) and the Software “Kubios HRV”. The first measurement is after waking up at 8 o’clock in the morning at complete rest (see Figure 1). The second measurement was made after prolonged moderate walking (12 km) and consumption of 4 standard instant coffee cups (see Figure 2). The comparison shows that the stress-index is significantly higher after the combination of exercise and instant coffee. In our case you can compare the other parameters of (PRV) too [3,4].

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Inflamyar™ Possesses Anti-Inflammatory Effect on Human Immune Cells and Cytokine Expression In Vitro  Biomedical Journal of Scientific & Technical Research

Integrated cancer patients profiling using combinations of PDC-PDx-Omics technologies are receiving growing scientific interest as a strong approach for clinical decisional workflows leading to personalized treatment. Nonetheless enforcing such workflows requires extensive collection and extended availability of the patients bioasset (specimen plus personal health and genomic data). However, biobanking and data collection from a large number of individuals bear both cost sustainability and ethical issues limiting the adoption of deep profiling workflows. These hindrances are linked to the cost and limited sharing of the fragmented patient data/specimen throughout the healthcare providers and 

medical research systems along with the challenges in attracting large numbers of informed and consenting patients in biobanking programs, as they are offered today Starting from the game-changing potential in the inclusion of PDC-PDx-Omics based and A.I.-driven decisional workflows in routine precision oncology, the present article considers the practical obstacles for the use of this approach in current practices. Furthermore, we analyze the present trends in the type of operational environments used to deliver PDC-PDx-Omics-based PGM services and provide new perspectives on the potential adoption of a non-profit, expert-patients-forpatients- driven, A.I.-backed, biorepository-CRO operational model towards attaining financial sustainability, wider service access and ethically compliant deep patients profiling towards effective cures.

Motor-Unit Recruitment Plays an Important Role in Determining the Relationship Between Muscle Force and Force Variability by Wan X Yao* in Biomedical Journal of Scientific & Technical Research https://biomedres.us/fulltexts/BJSTR.MS.ID.001722.php

Literature shows that force variability increases when force levels increase. However, this constant increase occurs only to a certain point (e.g., at around 50% of maximum voluntary contraction (MVC) and 80% MVC). After this point, the increase of force variability either slows [1,2] or stops [3-5]. The potential underlying mechanism accounting for the changing rate of increase in force variability is discussed in this brief review. It concludes that among several factors, motor-unit recruitment appears to be the most important factor in determining the relationship between force and force variability although both motor unit discharge rate variability and synchronization have a significant impact on force variability as well. Force variability has been observed across many studies where people attempt to produce a target level of force [1,3-10]. Recently, Christou et al. [1] examined participants performing an isometric leg extension and found that force variability increased almost linearly as the level of force increased up to 60% MVC. After this point, force variability continued to increase, but at a much slower rate. Similar findings were also reported in a study with an isometric hand-grip tasks [10], and in a study with isometric abduction of the first dorsal interosseous muscle [2].Force variability and its outcome has traditionally been viewed as a by-product of perceptual-motor noise imposed on a deterministic signal [3,11-13]. However, a study by Slifkin & Newell [9] indicated that the variability of motor responses might not be caused by the perceptual- motor noise.

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Music Therapy Decreases Anxiety of Patients Undergoing Hematopoietic Stem Cell Transplantation (Controlled Randomized Study) by Carlos Antonio Doro* in  Biomedical Journal of Scientific & Technical Research https://biomedres.us/fulltexts/BJSTR.MS.ID.001593.php

Background: Hematopoietic Stem Cells Transplantation (HSCT) is a treatment realized to combat several neoplastic hematological diseases. This proceeding combines chemotherapy doses, radiotherapy and has a high level of toxicity which causes physical and physiological morbidities and psychological suffering to the patient.Methods: Objective - This study evaluates the impact of music therapy in anxiety expression in adult patients who were hospitalized to go under allogeneic hematopoietic stem cell transplantation (HSCT).Design: This study is categorized as a Randomized Controlled Trial. Participants: adult Patients (n=100); groups: Experimental Music therapy Group (EMG) adult patients n=50 Control Group (CG) patients n=50.Intervention: emotional disorders, altered cognition, leading the patient to a depression. In this context, music therapy was applied as a therapeutic resource that contributes with the patient's interaction. After, each music therapy session a Visual Analog Scale (VAS) was applied.Main Outcome Measure: Student tests for independent variables and Mann-Whitney for non-parametrical variable. The level of statistical significance adopted in all the scales was p<0,05.Results: The variable anxiety were, analyzed considering three studies: first session, last session and average session of music therapy sessions. (p=<0,001) in the comparison of the two groups was considered statistically significant.Conclusion: In this study the music therapy proved to be a strong ally in the treatment of patients undergoing allogeneic hematopoietic stem cells transplantation, decreases anxiety, providing bio-psychosocial welfare.

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Algae as the Sources of Food and the Other Nutrients by Madhu Agrawal* in Biomedical Journal of Scientific & Technical Research (BJSTR) https://biomedres.us/fulltexts/BJSTR.MS.ID.001288.php#

Algae are the typical eukaryotic organisms, which are at the lower level of the evolution. From them the evolution proceeds out in different directions. They have very diverse ranges of the thallus of the pigments. The chlorophyta are characterised by the formation of the chla A,chl B ,and the chl c and many other kinds of the pigments, theses accessory pigments sometimes makes the hiding of the main pigments and they are charterised by the differ kinds of the Name , theses name are the green algae, blue green algae, yellow algae and the golden algae, diatoms, red algae, brown algae.

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Review on Medicinal Value of Aloe Vera in Veterinary Practice by Gebremedhin Yohannes* in Biomedical Journal of Scientific & Technical Research (BJSTR) https://biomedres.us/fulltexts/BJSTR.MS.ID.001287.php#

Aloe vera is a plant with height of almost 60-100cm containing very short stem or stem-less long leaves and belongs to the family Asphodelaceae. The aloe vera or succulent has a long history of being used for medicinal purposes, dating back to ancient Egypt. Aloe species are widely distributed in the African and the eastern European continents, and are spread almost throughout the world. The plant leaves contains numerous vitamins, minerals, enzymes, amino acids, natural sugars and other bioactive compounds with emollient, purgative, anti-microbial, anti-inflammatory, antioxidant, antifungal, antiseptic and cosmetic values for health care. The leaves of Aloe barbadensis are the source of two different products with medicinal properties: a yellow latex-like juice obtained from the cells just beneath the epidermis of the leaves with laxative properties and the parenchyma, the inner part of the leaves consisting of a mucilaginous gel. Aloe vera leaves are typically subjected to a series of processing techniques including: Reception of raw material, Filtration, Hot processing and flash cooling, Cold processing, Addition of preservatives and stabilizers and Storage. Many biological properties such as anti-diabetic, anti-inflammatory, peptic ulcers, antitumor, anticancer properties, activity effects on the Immune System, adverse reactions, Laxative effects, wound healing, antiseptic, anti- stress, are contributed by inner gel of the leaves. A. Vera has various health benefits in animals. The A. Vera as the Wonder plant” is multiple from being an antiseptic, anti-microbial, anti-ulcer, anti-inflammatory agent, helps in relieving tumor and diabetes. A. Vera has been used externally to treat various skin conditions such as cuts and burns. It is attributed to its minimal side effects, highly effective treatment. However, further study guided by research on therapeutic and medicinal uses of aloe vera are required in order to advance knowledge and to reduce adverse effects.

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