#bioai

Issue date: June 25, 2025Verify Credential

ID: 721b4975-23e8-4c10-bb6a-d7022b40b68e

Source: medianama.com

Power and Promise of AI in Biological Sciences

OpenAI is actively preparing for the growing impact of AI in Biology, recognizing its potential to revolutionize medicine, public health, and environmental science, these models are already aiding researchers in identifying successful drug candidates for clinical trials. Future developments may allow for rapid drug discovery, vaccine design, sustainable fuel production, and treatments for rare diseases. However, this transformative capability brings with it critical dual-use risks—while AI can push scientific progress, it could also be exploited to recreate or develop biological threats if misused.

To address these concerns, OpenAI is implementing a comprehensive safety framework to govern the development and use of AI in Biology. The company anticipates that future models will soon reach a “High” level of capability in biology, according to its internal Preparedness Framework. In anticipation of this, OpenAI is focusing on prevention by incorporating early-stage safeguards and rigorous evaluations to ensure that capabilities do not outpace safety measures.

A Multi-Layered Approach to Biosecurity and AI

OpenAI is building a robust system to ensure responsible use of AI in Biology. This includes close collaboration with government bodies, national laboratories, and biosecurity experts. By consulting specialists in biosecurity and bioterrorism early in the development process, OpenAI has shaped its threat models, capability assessments, and usage guidelines. Human trainers with advanced degrees in biology have helped develop safer model responses, and domain experts are now stress-testing these systems through high-fidelity red-teaming exercises.

To limit access to potentially harmful information, OpenAI is training its models to reject or safely respond to dual-use biological requests. While the general public may only receive high-level summaries, vetted experts can access more detailed outputs under controlled conditions. System-wide monitors detect and block unsafe bio-related queries, triggering automated and manual reviews. Moreover, misuse of these models—particularly when related to biological risks—can lead to account suspension and, in serious cases, notification of law enforcement.

A defense-in-depth approach protects the core infrastructure, including access controls, threat detection, and egress monitoring. These strategies are already deployed in models like “o3,” which, while powerful, have not yet crossed the “High” threshold. Lessons from these deployments are continually refining OpenAI’s technical safeguards and human review systems for AI in Biology applications.

Looking Ahead—Collaboration for Global Biodefense

OpenAI recognizes that mitigating biological risks goes beyond securing its own models. The company will host a Biodefense Summit in July, bringing together global stakeholders—from governments to NGOs—to assess dual-use threats and explore how frontier AI can support critical biodefense efforts. This summit aims to foster collaboration around countermeasures, diagnostics, and biosecurity innovation.

Future plans include giving responsible institutions controlled access to advanced models to accelerate beneficial applications in biological sciences. OpenAI also advocates for stronger infrastructure beyond AI, such as improved nucleic acid synthesis screening, early pathogen detection, and biosecurity startups. With the intersection of AI and biology rapidly evolving, OpenAI believes a shared commitment to safety and innovation will be essential.

Ultimately, the company emphasizes that AI’s role of AI in Biology must be guided by responsibility, vigilance, and global cooperation to ensure that its benefits are harnessed while minimizing potential threats.

Para alcanzar una civilización de tipo 1 según la escala de Kardashev, que es una medida de la capacidad tecnológica de una civilización basada en su capacidad de aprovechar la energía disponible, la humanidad necesitaría desarrollar tecnologías avanzadas en varios campos.

En primer lugar, la humanidad debería lograr una gestión eficiente de la energía, mediante el uso de fuentes renovables y limpias. También se necesitaría una tecnología avanzada de almacenamiento de energía para poder aprovecharla de manera más efectiva.

Además, sería necesario desarrollar una tecnología avanzada de transporte que permita viajar a velocidades cercanas a la de la luz, para poder explorar el universo y colonizar otros planetas.

En cuanto a la tecnología de la información, se necesitaría desarrollar sistemas de inteligencia artificial avanzados para poder automatizar muchas de las tareas y procesos que realizamos actualmente, así como para facilitar la toma de decisiones.

También sería importante desarrollar tecnologías avanzadas en el campo de la biotecnología y la medicina, para mejorar la salud y la longevidad de la población.

En resumen, para alcanzar una civilización de tipo 1, la humanidad necesita desarrollar tecnologías avanzadas en múltiples campos, incluyendo la energía, el transporte, la información, la biotecnología y la medicina.

Inglés.

Write what technology humanity needs to reach type 1 civilization

To achieve a Kardashev Scale Type 1 civilization, which is a measure of a civilization's technological capability based on its ability to harness available energy, humanity would need to develop advanced technologies in various fields.

First of all, humanity should achieve efficient energy management, through the use of renewable and clean sources. Advanced energy storage technology would also be needed to be able to harness it more effectively.

In addition, it would be necessary to develop advanced transportation technology that allows travel at speeds close to that of light, in order to explore the universe and colonize other planets.

Regarding information technology, it would be necessary to develop advanced artificial intelligence systems to be able to automate many of the tasks and processes that we currently carry out, as well as to facilitate decision-making.

It would also be important to develop advanced technologies in the field of biotechnology and medicine, to improve the health and longevity of the population.

La creación de ficción RPG (Role-Playing Game) con IA (Inteligencia Artificial) es una de las áreas de aplicación más emocionantes de la IA en la nueva revolución industrial 2.0. La creación de mundos de ficción, personajes y tramas atractivas para juegos de rol es un proceso complejo que requiere mucha creatividad y habilidades de escritura. Con la ayuda de la IA, los desarrolladores de juegos pueden automatizar algunos de estos procesos para crear experiencias de juego más inmersivas y emocionantes.

Una de las formas en que la IA puede ayudar en la creación de ficción RPG es generando contenido automáticamente. Por ejemplo, los desarrolladores pueden entrenar una red neuronal para generar diálogos y descripciones de personajes en función de ciertos parámetros, como la personalidad del personaje, el tono de la conversación y el contexto en el que se encuentra. Esto puede ayudar a los desarrolladores a crear personajes más detallados y realistas y mejorar la experiencia general del juego.

Otra forma en que la IA puede ayudar en la creación de ficción RPG es en la toma de decisiones. Los juegos de rol suelen involucrar decisiones complejas y ramificaciones en la trama basadas en las elecciones del jugador. Los algoritmos de aprendizaje automático pueden ayudar a los desarrolladores a diseñar un sistema de decisiones que responda de manera inteligente y realista a las elecciones del jugador. Esto puede hacer que la experiencia del juego sea más inmersiva y emocionante, ya que el jugador sentirá que sus elecciones tienen un impacto real en la historia.

En resumen, la creación de ficción RPG con IA es una de las áreas más emocionantes de la nueva revolución industrial 2.0. La IA puede ayudar a los desarrolladores de juegos a crear mundos de ficción más detallados, personajes más realistas y tramas más emocionantes. También puede ayudar a los jugadores a sentir que sus elecciones tienen un impacto real en la historia del juego, lo que puede mejorar significativamente la experiencia general del juego.

Inglés

The development of Fiction RPG with AI.

The creation of fiction RPG (Role-Playing Game) with AI (Artificial Intelligence) is one of the most exciting application areas of AI in the new industrial revolution 2.0. Creating compelling fictional worlds, characters, and plots for role-playing games is a complex process that requires a lot of creativity and writing skills. With the help of AI, game developers can automate some of these processes to create more immersive and exciting gaming experiences.

One of the ways that AI can help in the creation of RPG fiction is by automatically generating content. For example, developers can train a neural network to generate dialogue and character descriptions based on certain parameters, such as the character's personality, the tone of the conversation, and the context in which it is found. This can help developers create more detailed and realistic characters and improve the overall game experience.

Another way that AI can help in the creation of RPG fiction is in decision making. Role-playing games often involve complex decisions and plot branches based on the player's choices. Machine learning algorithms can help developers design a decision system that intelligently and realistically responds to player choices. This can make the gaming experience more immersive and exciting as the player will feel like their choices have a real impact on the story.

"We shouldn't be here," she muttered to herself, under her breath. She rubbed her hands up and down her arms, trying to chase away the goosebumps. She could feel her heart pounding in her ears--it was strange. Her heartbeat was regular, regulated; she'd never felt this sensation before. Fear--that's what this was. Absolute terror. "I shouldn't be here." 

"What're you nattering on about now, Ellie?" 

Ellie shrugged, flicking on her flashlight and shining it on the wide, empty street before them. "This city," she whispered. Her tongue felt heavy in her mouth; it was hard to force the words out. "It feels dead." 

"It's a cemetery, of course it's dead," Joe rolled his eyes.

Katie shrugged, adopting Ellie's whisper when she spoke up. "It does seem weird that these people would've gone through all the trouble to build a city just to house their dead in." Swinging her flashlight to illuminate an empty bakery with fake goods displayed in a window case, she shuddered. "I mean--these were an advanced people, they were space colonizers. It seems weird that they'd be so superstitious." 

"We shouldn't be here," Ellie repeated, unable to stop the words from tumbling out of her mouth. She agree with Katie. This place was weird, and it felt dead just beyond being a city built to for the dead. There was a heaviness in the air that made it difficult for her to walk, like her joints hadn't been oiled. "I feel like it's draining the energy out of me," she muttered. "We shouldn't be here."

"Chill, El," Joe scowled, but Ellie could tell he felt the need to be wary, too. Katie was more sympathetic. She rested a hand on Ellie's shoulder and squeezed. 

"There's no need to worry," she assured Ellie. "We charged you up right before we left the ship--" she pressed into Ellie's shoulder to bring up the power display. "See? You're at a hundred--Joe!" 

Ellie blinked blearily. "A hundred joe?" she mumbled, right before she lost all power. 

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