#active site

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A GIF created by the Amoeba Sisters demonstrating how a substrate binds to the active site of an enzyme.

enzymes: catalysts/chemical agents that speed a reaction without being consumed/produced by the reaction

works by lowering the activation energy of a reaction

99% of enzymes are proteins in structure - 1% are ribozymes made of DNA

most enzymes end with the suffix -ase

Enzyme combines with substrate (molecule the enzyme will work on) and a catalytic reaction takes place - forms a product. The enzyme can then be recycled and used for a later reaction.

activation energy: amount of input energy needed to start a chemical reaction

active site: region of the enzyme to which the substrate binds

allosteric site: portion of the enzyme to which a regulator will bind

NOT the same as the active site!

effect on enzyme may be stimulatory or inhibitory

feedback inhibition: when the end product of a biological pathway inhibits the activity of an enzyme involved in that pathway

cooperativity: different from allosteric regulation - enzyme contains multiple subunits. 

when regulator binds to one subunit, the rest follow course and a conformational change in the enzyme's shape takes place

Do you want to know my theory?

Lock and key theory.

A girl’s heart is like an enzyme (middle bit of the heart is the acitive site).A complete contrast to that is a man’s heart which can be compared to a substrate.

One specific substrate can fit to one specific enzyme.An active site has only one particular substrate that can fit like a glove.

When the reaction happens both hearts lock themselves to each other. One blood.

One soul.One heart.