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Drug development is a process that starts with the idea for an effective treatment, goes through stages of research and testing, and ends with a successful drug that can be sold by a large pharmaceutical company. The drug development process depends on having the right people in place. These people include scientists and engineers who develop your blueprint for making drugs. In the early stages of drug development, many different types of people are involved in this process.

Luminex BioPlex Bead Array System offers easy, affordable, and accurate labeling with a broad range of cytokines and antigen-specific detection solutions. A unique approach to diagnostics, Luminex BioPlex Bead Array System is ideal for single-bead based phenotyping applications whenever results require high sensitivity, user-friendly results and labeling efficiency.

While bioanalysis enables us to see things that are not visible to the naked eye, this is still a subjective process. Developing and validating bioanalytical methods require a lot of knowledge, experience, and resources. Without our experts helping you along the way, you would never get there.

Toxicokinetics studies are essential to the success of drug development, because they help to identify the toxicities of compounds and inform safer compounds that can be used in future development. In addition, toxicology studies provide information about the interaction of drugs with other pharmaceuticals and their action mechanisms to allow for informed decisions on how best to conduct studies related to toxicity in human subjects. We offer a broad range of toxicology studies  in drug development pipeline to help your company select the right approach.

Luminex has announced a resource transfer to increase the effectiveness of its bio-plex bead-based multiplex platform, which combines antigen capture and chemiluminescent detection into a single lab on chip (LOC). The resource transfer will enable Luminex to support up to five simultaneous immunoassays using the same sample.

If you're a pharmacist or work for an online pharmacy, chances are you need to know how to analyze medicines. That's why the team at the Natural Chemistry Department created these tools, which aim to streamline your life and make handling drugs.

An efficient multi-orbital mode for combination LC-MS/MS peak generation was developed as part of the Nebiolab platform. The negative and positive modes utilize different ions to generate a highly resolved protein spectrum. This method can be used in other analyte determination techniques such as MSn, QqQ and standard injection based MSn.

In the Drug Research and Development Laboratory, a ULT Freezer is a thermoelectric refrigeration system that takes advantage of the physical property of natural convection to cool or heat a liquid in vacuum. ULT Freezer is used for storing various materials like drugs, chemicals and biological samples at low temperature. It can be deployed in Research & Development laboratories, pharmaceutical companies manufacturing research and development leading to new product development and launches, law verification as well as drug manufacturing facilities. To know more visit here: https://www.nebiolab.com/how-to-use-ultra-low-temperature-ult-freezers-in-drug-rd-laboratory/

The matrix effect in LC-MS is the correction of peak elution factors by adjusting the injection volume. In this way, a concentration peak may be corrected to represent a concentration equal across all the channels used to collect samples thus allowing for normalization of retention times among channels and improving efficiency.  In this Blog, we discuss what is liquid chromatography mass spectrometry matrix effect and how to reduce it. Visit now! https://www.nebiolab.com/what-are-matrix-effect-in-liquid-chromatography-mass-spectrometry/

A drug's bioavailability and bioequivalence determine its effectiveness. In other words, if a product is not bioavailable, it cannot be absorbed by the body, and if it is not bioequivalent, the inactive ingredients are processed by the body for a longer period of time than intended.

In today’s healthcare environment, pharmacokinetics (PK) are a critical factor when dealing with drug efficacy and dosing adjustments. Our pharmacokinetics services will help you provide the best care to your patients by helping you understand how your medications work, how they're broken down in the body and why this is important for healthcare providers.

Toxicology studies are a key component of drug development. They aid in the understanding of potential adverse effects, mechanism of action and possibly finding a safer alternative for treatment. Studies ensure that new drugs are safe for patients and do not affect a person's health negatively.

Ultra-low temperature freezers (ULTs) are the preferred temperature control unit for use in the drug R&D laboratory. They have the ability to maintain a food or pharmaceutical sample at temperatures from −120°C to +20°C. This is not only clinically safe, but in many cases will produce better quality results due to better stability of samples found in ULT-specific associated products.

The temperature range of these freezing systems allow for slow cooling after incubation and cell culturing, which preserves cellular integrity prior to freezing and then room temperature storage until needed for workup and analysis.

This guide provides an overview of toxicology studies that can be conducted by an independent contract research organization using IND-enabled Good Laboratory Practice (GLP) under an approved test registration. The Expert Panel for Toxicology Studies Using IND-Enabled GLP have drawn upon their experience and knowledge to develop guidance on the design, performance, and reporting of these types of studies.

A toxicology study using an IND-enabled Good Laboratory Practice (GLP) program can be complicated and confusing. In this guide we will explain the process step by step, and make things easier for you!

Bioanalytical Laboratories: Understanding Good Laboratory Practices (GLP) is a unique three-day program that focuses on the requirements of good laboratory practices and how they impact quality and regulatory compliance. The course covers topics such as how to develop a GLP compliant laboratory, aspects of validation and acceptance testing, statistical methods and data interpretation in support of GLP studies, as well as a wide range of other important topics.

To know read more visit here: https://www.nebiolab.com/good-laboratory-practices-for-bioanalytical-laboratories/

"Based on cellular function and activity, in-vitro cytotoxicity and cell viability assays for drug discovery and fundamental research. "

·         Cytotoxicity assays are designed to assess the ability of specific drug compounds to destroy an organism's healthy cells.

·         Cytotoxic compounds can cause either accidental (necrosis) or programmed cell death (referred to as apoptosis).

·         Cytotoxicity assays are used to evaluate the safety profile of a drug candidate during the nonclinical and clinical research phases of drug discovery and development.

“In-vitro biochemical assay for detecting, quantifying, and studying the binding or activity of biomolecules such as enzymes. “