The Pilot was filmed in March, 1993. Here's a 2016 perspective on the subject of chemistry from David, Gillian, and Chris. Also, I included an early critic's observation.
Anderson: I feel like the chemistry was there from the very beginning. That was the foundation of it. After so many notes asking us actors to take looks at each other—after doing that I don’t know how many billion times—you start to get the idea that was what they were playing to.
Duchovny: That word always perplexes me, because Gillian and I never worked on our chemistry. We don’t come in, in the morning, and go, “How’s the chemistry? I really need some coffee with my chemistry this morning.
Anderson: We didn’t know each other at all, but for some reason there was something in the room between the two of us that wasn’t there with others. To a degree, you can manufacture that as actors, and you have to most of the time, but for some reason there was something tangible and palpable that existed between us, right then.
Showrunner Chris Carter Friday during a Television Critics Association panel for the revival series on Fox. "So they were cast separately, we didn't know whether or not they would have chemistry. … It wasn't until the day they were both in Mulder's office, and they both just lit up, and it's been the same ever since.”
"On-screen chemistry is a difficult thing to achieve, but Duchovny and Anderson have it in spades. From the moment they first meet, it's as though they have always been a duo"—Matt High, Den of Geek, 1993
titsay
yousharknotpass
izzy806
amandla
pixelskylines
2087
turnnoffyourmind
