Taken by illness (implied to be kind of sickly?)
Taken by Gloom sickness while exploring beneath the castle for sheikah relics
Assassinated by the yiga clan (who go on to try to kill Zelda and Link)
Weakened after passing her power to Zelda (no magic moms allowed)
Poisoned by a follower of Ganon (the vaguely evil chancellor who ate Evil cake?)
Involved in an accident involving the guardians/sheikah tech (covered up?)
Killed while protecting Zelda (which she doesn't remember due to age and trauma)
Smth about how the spirit of Hylia has to pass from mother to daughter...
Relied on being the host of the Triforce to stay alive, until Zelda needed it
was involved in a high-speed carriage collision & had no phone to call 911
royal cook put the wrong type of mushrooms into her morning omelet
Other (insert your hc here/in the comments/asks idk)