Karla Boncompagni

As nerve cells involved in long-term firing in the pain circuit continue to fire, the brain real estate dedicated to processing pain signals rapidly expands. Local nerve cells from other functions that are not being used as much are reassigned to process pain. Not only does pain become more persistent, but other local functions like problem solving, planning, empathy, autobiographical memory, sensory processing, emotional stability all become less active and are degraded.

This shows how the brain's pain network expands when pain transforms from acute to persistent. It also demonstrates that when the brain responds by increasing the release of GABA, the main inhibitory neurotransmitter, from the insula to the amygdala, pain perception is shut off.

Autumn colour flowers are just gorgeous! Flores com as cores do outono são lindas! . . . #autumnflowers #margaridas #floresdeoutono #almostoctober https://www.instagram.com/p/BoEvGMPHbfw/?utm_source=ig_tumblr_share&igshid=1spgcq3wt3ju1

Green resilience . . . #urbangreen #greenresilience #greenarchitecture #urbannature (at London, United Kingdom) https://www.instagram.com/p/BntvxtoHXB8/?utm_source=ig_tumblr_share&igshid=cctxilodn450

Relaxed Wednesday 🛀 . . . #relaxeddayoff #relaxedwednesday #bubblebath #clarins https://www.instagram.com/p/Bmx8zhInQ66/?utm_source=ig_tumblr_share&igshid=1cmqvl3lk5cu5

feels like autumn already 🍂 💕 . . . #feelslikeautumn #lookingfoward #autumn-feeling #almostautumn #autumnpantone https://www.instagram.com/p/Bmf0I-yHz4L/?utm_source=ig_tumblr_share&igshid=ql35le8umbos

Looking forward for the week ahead. . . . #Repost @antonio__soares #lookingfoward #lookingfowardfortheweek #bluesky

Perfection . . . #justperfect #flower_perfection #flowerperfection #flawless #happyfriday #Repost @aquietstyle 😱💕

Simplicity 💚 . . . #Repost @debora.carminati #minimal #minimalchic #minimalism #essential #essence #walldecor #streetphotography #streetstyle #simpley_perfection #simplicity #nature_prefection

Cargo Trousers & Sandals 💕 . . . #cargotrousers #summersandals #summerlook #instalook #instainspo

The perfect A team Handbag & Silk Bandana . . . #whitagram #totebag #silkbandana

Sarcasm is an art and I have mastered it well 🙈

Holiday Look . . . #italianmood #italybreak #familyholiday #summer2018 #pinterestinspired #instalook

Herbs and Dinner 🌿 . . . #herbs #basil #healthdinner (at London, United Kingdom)

Knock knock ✊🏻✊🏻✊🏻 Gorgeous door detail . . . #knocking #heavensdoor

#butterflybeauty #summerafternoon #sundayvibes 🦋 (at The Green Man)

Never go wrong with basics indeed👌🏻 . . . #instainspo #Repost @sensof_style