Karolina

A venn diagram with three circles, labeled "estrogen would fix him," "estrogen would make him worse," and "estrogen could not save him (but it'd be really funny)."

In the "estrogen would fix him" section are:

Kirito from Sword Art Online.

Mister Priest from Make the Exorcist Fall in Love.

Cloud from Final Fantasy 7.

Don Quixote.

In the overlap between "estrogen would fix him" and "estrogen would make him worse" are:

Enciodes Silverash from Arknights.

Denji from Chainsaw Man

In the "estrogen would make him worse" section are:

Light Yagami from Death Note.

Izuku Midoriya from My Hero Academia.

In the overlap between "estrogen would fix him" and "estrogen could not save him" are:

Seto Kaiba from Yu-Gi-Oh.

Sanji from One Piece.

In the "estrogen could not save him" section are:

Shinji from Neon Genesis Evangelion.

Char Aznable from Gundam.

Quatro Bajeena from Gundam.

In the overlap between "estrogen would make him worse" and "estrogen could not save him" are:

Zenos from Final Fantasy 14.

Laios Touden from Dungeon Meshi.

Lazurite Roy from Arknights.

And finally, in the dead center of the venn diagram, are Shirou Emiya from Fate/Stay Night and Kim Dokja from Omniscient Reader's Viewpoint.