g o d o i d

'Shilaya Vilarias' by Jeff Dekal.

“Intuition is perception via the unconscious that brings forth ideas, images, new possibilities and ways out of blocked situations.” — C.G. Jung

A new approach to building 3D molecules for better drugs

A report in the journal Science from researchers in the UW–Madison Department of Chemistry represents a significant advance in making the types of molecules needed in drug development. Molecules with three-dimensional complexity are known to be better for drug development than flatter molecules, but accessing molecular complexity has historically been challenging. The work in this paper sets the stage for addressing this long-standing problem. The research reported in this paper illustrates the interplay of teaching and scholarship at UW–Madison. Faculty member Dan Weix, a leader in the invention of new chemical reactions, was struck by the potential of a reaction known as "decarbonylation" to address the central challenge of creating more molecules with three-dimensional complexity while revisiting classical studies as part of teaching an advanced course to undergraduate and graduate students.

A recent New Scientist cartoon.