In the End it All Comes Down to You

T1 script has a scene of Frigga telling Odin that it's ok to make Thor king despite him clearly not being ready for this role because Loki will be there to guide and help him. And, looking at the relationship the brothers share, it's so clear that Loki was always raised with this expectation of taking care of Thor. Thor ALWAYS runs to Loki with his problems, even when they haven't talked in over a year, Thor vents to Loki, Thor decides where they're gonna go and what's they're gonna do, the people they both hang out with are Thor's friends, etc. Loki doesn't do any of this, in fact, I cannot recall a singular time Loki would ask for help/bring up his problems around Thor. Moreover, each time Loki expresses any kind of an emotional need or acts unhappy, Thor gets angry, and even violent. Tell me what kind of dynamic it portrays to you. Damn, Thor doesn't even look at Loki while talking to him in T1. ("Never doubt I love you" - "Thank you").

Then there's Odin and Frigga consistently holding the fact they "love" him and, in Odin's case, "didn't let him die" over his head, in both T1 and TDW, to guilt him into obeying them and acting the way they want him to, to remind him that he's "obligated" to be grateful and helpful.

The Other tells him that he owes Thanos for the "great purpose" and his own enslavement.

Then there's Mobius telling him that he was born for the sake of the avengers' success and "to make people into the best versions of themselves". He also holds the "I didn't lat you die" card over his head and tortures him for "being a bad friend" for "running away", etc.

Like, at any given opportunity, Loki is reminded that his existence is in service of other people, he's discouraged from having feelings, or even acting in self-preservation/making decisions that do not result in someone else directly benefiting from.