Multiple Endocrine Neoplasia
MEN 1 = Wermer’s Syn
Pituitary
Parathyroid
Pancreas (gastrinomas, peptic ulcers)
Make sure to check serum Ca++ esp if kidney stones/peptic ulcers
So for MEN1 I’m gonna relate it to Kuroko no Basket’s Akashi. He is has the Emperor’s Eye which means he is the EMPEROR and they have all the things - thus Akashi has all 3 P’s - Pituitary, Parathyroid, and PANCREAS THE FORBIDDEN ONE.Â
MEN2A = Sipple’s Syn
Parathyroids
Pheochromocytoma
Medullary thyroid cancer
Inc amyloid and inc calcitonin
MEN2A = Himuro because 2B is the freaking giant Murasakibara. He loves the pheochromocytoma with all the catecholamines, metanephrines, palpitations, and sweating. It’s almost like he has a thyroid problem. He also gets PARAnoid (parathyroid), kidney stones and increased amyloid when he’s away from his boo Murasakibara.Â
MEN2B
Pheochromocytoma
Medullary thyroid cancer
Marfanoid body habitus
Mucosal neuromas - tongue tumors
MEN2B is definitely Murasakibara. He’s got the huge Marfanoid like body. He’s got the tongue tumors what with all the junk food he eats. He also loves the pheochromocytoma because Himuro like it. He also shares the possibility of getting that medullary thyroid cancer because he’s xoxoxo with Himuro.
MEN Syndromes are all Autosomal Dominant - thus all the dominant BB players that and they’re all MEN
MEN1: 3P’s = All the P’s = Emperor takes all
MEN2A: 2P’s = gets some parathyroid stuff and shares pheo and thyroid with 2B
MEN2B: 1P, Giant with an oral fixations but shares medullary thyroid cancer & pheo with 2A
