#tight junctions

Meeting Points

Greater understanding of the molecular regulation of epithelial cell structure, cytoskeletal organisation and the tight junctions between them – key role of protein CGNL1 (paracingulin) in recruiting another protein CAMSAP3 to junctions revealed

Read the published research article here

Image from work by Arielle Flinois and colleagues

Department of Molecular and Cellular Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Journal of Cell Science, May 2023

Human Umbilical Mesenchymal Stem Cells Decreases Dextran Sulfate Sodium-Induced Colitis in Mice

Ulcerative colitis is one of the Inflammatory Bowel Diseases (IBDs) that features chronic inflammation of the large intestine. This is an autoimmune disease that features constant attacks by the immune system on the intestinal mucosae, and the inner layer of the large intestine undergoes constant damage and healing, which increases the risk of the patient to developing colorectal carcinoma.

Mesen…

Me: Hey Dad, I need help with my homework. I don't know any examples of where I can find tight junctions, desmosomes and gap junctions in the human body.

Dad: Ok. We can start with tight junctions.  Where do you think there are tight junctions in the body?

Tight Junction

Tight junctions, or zonula occludens, are the closely associated areas of…

Because it's more fun in Med School.. hahaha