#thehoundsofbaskerville

Our anniversary rewatch continues, and yesterday my brother and I finished season 2 of 'Sherlock'. Well, it's still my least favourite, although I would not say that it was bad. It was simply very difficult to say something new on three most iconic subjects of the original ACD works - Irene Adler, the Hound of Baskerville and Moriarty. And although the characters and actors were great, the James-Bond-style plot was not my thing. 'The Reichenbach Fall' is still the best of the three, and the disappoitment with Moriarty was recompensed with the great acting of Cumberbatch, Freeman, Gatiss and Brealey. 'The Hounds of Baskerville' failed to scare and lost the charm of the original novel, but it was inevitable in the modern setting. On the other hand, the constant presence of Sherlock Holmes in this episode saved the day - hats off to Benedict Cumberbatch once more. 'A Scandal in Belgravia' had many interesting ideas, but the details ruined everything, and I still can't stand Irene Adler (so I was very happy to kill her off in my own fanfic - after all, as Steven Moffat put it, it's what fanfiction is for).

Deliriants are typically anticholinergic agents which block the binding of the neurotransmitter acetylcholine to its receptor, causing the symptoms such as not being able to distinguish hallucination from reality.  Additionally, some anticholinergics are toxic and if overdosed on them they may cause death.  Tropane alkaloids are a class of compound with properties that act as anticholinergics.  These are chemical compounds comprised of bicyclic alkaloids and tropane rings.  The most common of these are scopolamine, atropine and hyoscyamine.

Once you've ruled out the impossible, whatever remains, however improbable, must be true.