#saggital

(via The Speech Chain: A Vintage Illustrated Guide to the Science of Language | Brain Pickings)

This patient was diagnosed with herpes simplex encephalitis (HSE), MRI showed signal intensity changes in the left temporal lobe, this sagittal T2-weighted image in also shows the hyperintense lesion in the temporal pole on the left side, in HSE, the virus has a predilection for the temporal lobe, HSE is the most common cause of sporadic lethal encephalitis, the cause of this infection is herpes simplex virus 1 in adults and herpes simplex virus 2 in neonates, neonatal infection is acquired perinatally, patients usually present with viral prodromal symptoms, including fever, lethargy, confusion, delirium, headache and convulsions, brain involvement is usually unilateral and the temporal lobe is most commonly affected, HSE must be distinguished from herpes simplex meningitis, which has a benign clinical course, CT scans may depict a hypoattenuating temporal-lobe lesion, which generally appear 3 days after the onset of symptoms, enhanced CT scans may also show hemorrhagic areas and enhancement, mass effect with compression and displacement of ventricles may be seen, MRI scanning shows low signal intensity in T1, high signal intensity in T2 and gadolinium contrast enhancement