#pseudouridine structure

PseudoUridine (abbreviated by Ψ) or 5-ribosyluracil, is an isomer of uridine (U), and unlike uracil in uridine, which is linked to ribose by a carbon-nitrogen bond (C1-N1), uridine and ribose of Ψ are linked by a carbon-carbon bond (C1-C5). Uracil and ribose are connected by a C1-C5 bond in Ψ, so its structure is more flexible and has an additional site for hydrogen bonding than uridine, and the overlap effect in RNA is higher than that of uridine.