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Carbapenem
1 Definition
Carbapeneme sind Antibiotika aus der Gruppe der Beta-Laktame.
2 Chemische Struktur
Carbapeneme weisen im Gegensatz zu anderen Beta-Laktamen im Fünfring des Beta-Laktams ein Kohlenstoff-Atom statt Schwefel auf. Ursprünglich wurde die Leitsubstanz der Carbapeneme, das Thienamycin aus der Pilzart Streptomyces cattleya isoliert. Da Thienamycin jedoch im Organismus instabil ist, werden…
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