#prempro

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Transdermal vs. Oral Estrogen Part Two by Jeffrey Dach MD In part one, we explored the studies which show that transdermal estrogen delivery is preferable over the oral pill form of delivery.  In part two of this series, we will explore further the…

A federal appeals court has sided with two women who developed breast cancer after taking the hormone therapy drug Prempro. The women alleged that Wyeth failed to adequately warn that the use of Prempro increased their risk of breast cancer.

The 8th U.S. Circuit Court of Appeals said a federal magistrate judge abused his discretion when he blocked expert testimony from a doctor on behalf of Pamela Kuhn and Shirley Davidson.

Pamela Kuhn and Shirley Davidson were prescribed Prempro, a hormone therapy drug comprised of estrogen and progestin. Kuhn took Prempro for three years and twenty-eight days; Davidson took it for one year and nine months. Both women developed breast cancer and filed separate lawsuits against Wyeth in the Western District of Arkansas.

Prempro is used to treat symptoms of menopause, including vasomotor symptoms and vaginal atrophy.

Wyeth Inc. suffered a setback as a U.S. jury has awarded $4 million to the breast cancer survivor, who had claimed to have developed the disease after taking the hormonal therapy medication Prempro, manufactured by Wyeth, which is now part of the Pfizer group. 

Blaming Wyeth, the jury found that the plaintiff’s invasive breast cancer had developed due to the hormone-replacement drug Prempro. Announcing the verdict that Prempro was an “unreasonably dangerous product,” the jury found Wyeth’s conduct reckless and granted punitive damages to the plaintiff. 

The jury found that the Prempro manufacturer failed to properly warn users of the risks of using the drug. Criticizing Wyeth for misrepresenting what it did know, the jury pronounced the verdict in the product liability lawsuit in favour of the plaintiff.

The hormone therapy medication Prempro contains a blend of progesterone and estrogen and is prescribed for the treatment of menopause, including mood swings and hot flashes. The drug became extremely popular when it was marketed for sale. 

In 2002, a study conducted by the U.S. National Institutes of Health startled everyone by revealing the drug’s link to cancer. By then, over 6 million women had taken Prempro, unaware of its side effects.

Dec. 6 (Bloomberg) -- Pfizer Inc. must pay $72.6 million in damages to three women who said they developed breast cancer after taking the company’s menopause drugs, a Philadelphia jury decided.