Hyponatraemia is a state of decreased serum sodium (normal range 133-146 mmol/l). It is usually caused by an increase in water rather than a decrease in sodium itself.Â
Pseudohyponatraemia usually occurs in diabetics when they are hyperglycaemic. The increased glucose in their blood (which can be up to an insane 50mmol/l in HONK) increases it's osmolality. An increase in osmolality draws water from the intracellular space into the bloodstream.Â
Seeing as electrolytes are measured as concentrations rather than as gross amounts, this increased plasma volume means that the sodium is diluted, and so there are fewer mmols of it per litre. The patient will come out as having hyponatraemia, despite their being nothing wrong with their sodium control or their fluid control. They just have too much glucose.Â