#mitotane

Lysodren 500mg is a cancer medicine used to treat certain types of cancer, specifically adrenocortical carcinoma (a type of cancer that starts in the outer layer of the adrenal gland). It works as a anti cancer agent by destroying the cells in the outer layer of the adrenal gland, which are the cells that are most likely to become cancerous. 

Lysodren (mitotane) is a cytostatica that is used to treat certain types of cancer, specifically adrenocortical carcinoma and certain types of breast cancer. It works by inhibiting the growth and division of cancer cells, which ultimately leads to the death of the cells.

Lysodren (mitotane) is usually taken as a single daily dose, but the specific dosage will be determined by a healthcare provider based on the patient's specific needs. Normal incidental effects incorporate sickness, retching, looseness of the bowels, and loss of craving. It is important to note that Lysodren(antineoplastic medication) can cause serious side effects, including damage to the liver and kidneys, so it should only be taken under the close supervision of a doctor.

Lysodren is considered as an antitumoral medication different from most cytotoxic drugs in that it is specific to adrenal cancer cells, thus it has less general toxicity on the body. It is usually used in combination with other cancer treatments and close monitoring by a healthcare provider is needed as it can cause significant side effects.

Lysodren is not typically used to treat anaplastic lymphoma kinase (ALK) positive cancer. ALK positive cancer is a subtype of non-small cell lung cancer (NSCLC) that is characterized by a genetic alteration in the ALK gene. The ALK gene provides instructions for making a protein called anaplastic lymphoma kinase, which plays a role in cell growth and division. ALK positive cancer is treated with specific ALK inhibitors, such as crizotinib and ceritinib, which target and inhibit the activity of the ALK protein.

Le nuove terapie del carcinoma surrenalico, un tumore raro con altrettante rare opzioni farmacologiche

Il carcinoma adrenocorticale (ACC) è una rara neoplasia endocrina con opzioni di trattamento limitate. L’unica terapia fino a 30 anni fa era il mitotane, composto derivato dall’insetticida DDT e ritenuto in grado di uccidere selettivamente le cellule surrenaliche. Negli anni sono stati introdotti anche la doxorubicina, il cisplatino e l’etoposide con risultati discreti sulla sopravvivenza. Più…

In this article, we will discuss Mitotane (Clinical Pharmacology). So, let’s get started. Clinical Pharmacology Mitotane can best be described as an adrenal cytotoxic agent, although it can cause adrenal inhibition, apparently without cellular destruction. Its biochemical mechanism of action is unknown. Data are available to suggest that the drug modifies the peripheral metabolism of steroids…

In this article, we will discuss Mitotane (Dosage Overview). So, let’s get started. Indications Mitotane is indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Dosage The recommended treatment schedule is to start the patient at 2 to 6 g of Mitotane per day in divided doses, either three or four times a day. Doses are usually…

My Megan

Dear Mr. Vice-President,

“I’m sick, Mom.”

That whisper from my daughter’s lips hit my ears harder than the sound of fireworks on the 4th of July, 2004.

From the giddy laughter of the little neighborhood pyromaniacs as they ignited their pop bottle rockets to the cry from the kitchen that said, “Who made the baked beans?” sounds were swirling around me.  But my life as I knew it stopped…