The banana (Musa paradisiaca) exocarps have been a substantial source for maintaining human health. Banana peel extracts for antimicrobial properties can be of great significance in therapeutic treatments. This study aimed to evaluate the antimicrobial activity of banana exocarps among the selected pathogens. The collected data on antimicrobial assay were presented in means and the standard error of the mean was properly calculated for the zones of inhibition measured for the experiment. Among the test microorganisms, only the Gram-positive bacteria were sensitive to the ethanolic extracts of Lacatan (Musa acuminata C.) and Cardaba (Musa acuminata balbisiana) with the diameter zone of inhibition ranging from 15.30±3.72mm to 15.35±2.13 mm. The ethanolic extract of two varieties of banana exocarps showed various inhibitory effects against several microbial isolates. Highest inhibitory effect against S. aureus with 15 mm inhibition zone, followed by E. coli with no effect. The ethanol extracts of banana exocarps could be considered a good antimicrobial agent against both Gram-positive and negative bacteria to restore the synthetic medicines in the treatment of diseases caused by these microorganisms. The study suggested that the local tribes or ordinary people could explicitly continue utilizing this banana plant as a source of treatment.
