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Brain's Response to Mid-Life Surge in Cell Aging Starts or Ends Path to Dementia
IResearchers at The University of Texas Health Science Center at Houston (UTHealth) School of Dentistry and McGovern Medical School have discovered a previously unknown characteristic of brain-cell aging that could help detect late-onset Alzheimer's disease decades before symptoms begin.
The research is in Translational Psychiatry. (full open access)
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IL-33 Increases the Magnitude of the Tissue-Resident Memory T Cell Response in Intestinal Tissues during Local Infection
Abstract IL-33 plays an important role in the early programming of CD8 T cells; however, its contribution to the differentiation of tissue-resident memory T cells in vivo remains poorly defined. After infection of mice with Yersinia pseudotuberculosis, IL-33 expression was increased in the intestinal tissue, and this coincided with the expression of ST2 on T cells infiltrating the intestinal…
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PhD student, Pauline Schmitt, going the extra mile at her poster to exhibit her work on how #IL33 and #TL1A promote #ILC2 that súper express #IL9 and induce asthmatic features w/out allergen upon adoptive transfer into naive mice #AAI2019 The American Association of Immunologists - AAI Institut de Pharmacologie et de Biologie Structurale - IPBS #immunology (at San Diego Convention Center) https://www.instagram.com/p/BxX1ruCjHT4/?utm_source=ig_tumblr_share&igshid=iewej7gt1goh
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