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First Ibrance down the hatch. I hope this doesn’t suck as much as the Verzenio.
Also, I forgot to get a beer. I’ve been feeling well all day. I’ve been looking forward to a beer. I was practically drooling on the way home from the pharmacy, thinking it was finally Beer:30.
And then I straight-up forgot.
I poured myself some sparkling water.
So...here’s to healthy choices, I guess.
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How Expensive Is Palbociclib Ibrance
Generic PALBOCICLIB / Brand IBRANCE PALBACE 75mg / 100mg / 125mg Capsule is used to treat breast cancer. Palbociclib / Ibrance Palbace medication is also found to be effective in treating patients who have certain types of cancer in the breast (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) that have multiplied in other organs of the body along with breast. Palbociclib / Ibrance Palbace medicine is co-administered with other anticancer therapies of hormones.
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I am living with #metastaticbreastcancer . At the age of 26, I was diagnosed with Stage III #invasiveductalcarcinoma. After being ignored and pushed aside by 8 doctors' offices, then having to wait over a month for an ultrasound, mammogram, and emergency biopsy, they realized that, despite my age, health, and lack of family history, the large mass that could be seen through my chest was more than a cyst. I had a 6cm tumor in my right breast that was so large, I was inoperable. My doctors would have to attempt to shrink it with an aggressive chemotherapy regimen (#Taxotere, #Adriamycin, #Cytoxan) prior to a #mastectomy, #radiation, and ten years of hormone therapy. 32 lymph nodes were positive at the time of my surgery, meaning that the cancer was spreading. I completed radiation and started hormone therapy (#Tamoxifen) to keep my cancer from recurring. I was in menopause and told I was infertile. But while on hormone therapy, I ended up pregnant, and was blessed with a miracle child. I had great hope and many plans for the future. In 2017, I realized something wasn't right. My hip hurt terribly and I could barely walk. Physical therapy did not help, so I decided to see an orthopedist. MRI revealed that my cancer had returned and spread to my bones. Further testing revealed it had spread to my liver and pleura. I was five years out from my initial diagnosis. I had a total hip replacement and pelvic reconstruction surgery, radiation, and months of physical therapy to regain my ability to walk. My first line of treatment (#ibrance and #letrozole) failed within weeks, and I had major progression (cancer was growing, rapidly), taking anti-hormonal treatment off the table for me. I am currently on an oral chemotherapy treatment (#Xeloda), still hoping that I will have more days with my daughter. ~ Lindsay :::::::::: #stageivneedsmore #dontignorestageiv #metsmonday #sspw #shaysharpespinkwishes #dyingforacure #teamsspw #BeyondTheBreast #youngwomencananddogetbreastcancer #TeamWGL #livingbeyondbreastcancer (at Maryland)
Another Drug Bites the Dust!
New Story has been published on https://enzaime.com/another-drug-bites-dust/
Another Drug Bites the Dust!
Happy and concerned. This is how I have been feeling the past week, after meeting with my oncologist to discuss scan results.
The results of my scans were mixed. Bones look stable, which is wonderful, but my liver, is misbehaving. The lesions that have been on the liver, are shrinking, which is great news, but I have developed new lesions. Hmmmm….what is going on now?
My oncologist has two school of thoughts about the mixed scan results concerning the liver, and what might be taking place. The first is the cancer has outsmarted the Taxol, and has stopped working. This happens frequently with many drugs that are given to cancer patients. The second, and this is where we are concerned, the breast cancer has gone from being hormone receptive positive (ER+ PR+), to triple-negative. Hormone receptive positive breast cancer means that the cancer cells receive signals from estrogen and progesterone receptors, to promote their growth. Triple-negative breast cancer refers to breast cancer that does not express the genes for estrogen and progesterone receptors, or HER2. HER2 positive breast cancer tests positive for a protein called human epidermal growth factor receptor 2 , which promotes the growth of cancer cells. These cells have have a gene mutation that makes an excess of the HER2 protein. Because triple-negative cancer cells lack these protein receptors in hormone receptive and Her2 positive cancers, common treatments like hormone therapy and targeted therapies, are ineffective.
Due to the scan results, and the miserable side effects, Dr. M has taken me off Taxol. Bye, bye Taxol. Don’t let the door hit you on the way out! My side effects should subside…no red hot rash on my face, and other parts of my body, no nails falling off, no leaky eyes, no gastrointestinal problems, no neupogen shots and no weekly visits to Dana Farber! Feeling happy.
I have been put on two new drugs. The first is a type of oral chemo called Palbociclib, also known as Ibrance, and a hormonal therapy called Letrozole, also known as Femarra. Although each drug has it’s own side effects, they will be more gentle than Taxol. Yippee! Dr. M has a team of nurses looking into clinical trials as well for me to participate in.
I will be scanned in two months time. If the scans show no improvement, I will get another liver biopsy done to determine if the cancer has switched teams from being hormone receptive, to triple-negative. I am feeling calm about this matter.
Switching to more desirable news, I booked our Las Vegas vacation for Michaela and I. I am so excited to show her the sights and sounds that can only be found in Vegas. Mark and I are currently working on airfare and hotels for Max’s college trip to San Fransisco and Los Angeles. He plans to check out six schools. How exciting……but so far away!
I am bummed we are not getting the blizzard the meteorologists were thinking we might get in Massachusetts. It sure is cold though. If you are getting this major storm, please be safe.
Below is a photo of a whimsical mermaid I purchased last summer in Key West. Ah, Key West, so beautiful and WARM. She hangs out on my screened in deck, swaying gently back and forth, during a windy day.
Vegas, Baby,Time Came
New Story has been published on https://enzaime.com/vegas-babytime-came/
Vegas, Baby,Time Came
When the time came for my daughter, Michaela, to turn 21, I knew I wanted to take her to Las Vegas. She caught a bit of the gambling bug from the time she spent in the casinos on the cruise ships we sailed on (gambling age is 18).
Michaela turned 21 at the end of December. I suggested the trip to her in front of Mark. He did not say no. Hmmm….I thought, this is really going to happen! He thought it was a great idea. A fun mother/daughter trip to make fun memories.
Michaela would be on her college spring break in March, which is when we would take our trip. I booked the trip in January and chose a beautiful, contemporary resort smack dab in the middle of the Vegas strip. Michaela would fly home from GW, spend a couple of days with the family, and then she and I would fly to Las Vegas together.
About a week before Michaela arrived home, I started to become extremely fatigued. I was also feeling like I was coming down with a sinus infection. I saw my nurse practitioner at my primary care office, and she put me on an antibiotic because I did indeed have a sinus infection. The following day I was due to get blood work because since going on Ibrance, I receive blood work every two weeks.
In speaking with my nurse practitioner at Dana-Farber, after receiving my lab work results, I explained to her how tired I had been. She told me it was the Ibrance. The Ibrance has also been lowering my white blood counts, and this week was no different. I would receive another week off from Ibrance, which would be nice while I was on the antibiotic, and on vacation.
Because I was not feeling myself, I was becoming a bit nervous about traveling. It would be my first trip without Mark since I was diagnosed with breast cancer. Mark told me all would be fine, and that Michaela would take care of me. He would be right.
Michaela and I had an early flight, and only got 3 hours of sleep before our flight left, in part because it was daylight savings and we lost an hour. We did manage to get a good amount of sleep on the plane. Getting to Vegas was uneventful and with a quick Uber ride, we were at our resort. It was beautiful and super modern. All the controls in the room are controlled by an iPad. Michaela figured it out quite quickly, me, not so much. I accidentally shut off all of the lighting one evening at 3:30, I guess that really is the morning, while Michaela was showering…..I couldn’t stop laughing as I heard her screaming, and scrambled to figure out how to get the bathroom lights back on.
I won’t get into all the details, because what happens in Vegas….well, you know, but we played slots, black jack and roulette. We ate at some very nice restaurants, visited other hotels, and met some nice people. We stayed up very late! By our last day, we were both exhausted. We were ready to go home.
At this point I was not only tired, but feeling a bit weak. Michaela rolled both our suitcases through the airport. Our plane ride home was not the best. We got out of Las Vegas fine, but on the connecting flight to Boston, we were on the plane for 45 minutes before we were told to gather our belongings. It would be another 3 hours before we would depart again.
We arrived home very late. The following day I needed to go for blood work. My white blood counts had rebounded nicely, and I was able to begin the Ibrance, but at a lower dose. I think the reason I am starting to feel weak is because my red blood counts are now dipping. Sometimes, I feel like I just can’t get ahead.
In two weeks I receive scans to see how the Ibrance and Letrozole are working. Obviously, we’re hoping to hear good news. I usually have some inclination on how the scans results will be, but truthfully, this time I do not. We’ll know soon enough.
Meanwhile, my beautiful daughter and I had an awesome trip spending time with one another, creating wonderful memories. It’s those memories that help get me through the sad times of having metastatic breast cancer.
When I’m not feeling well, or frustrated with treatment side effects, or just want to burst into tears, I will remember shutting off the lights while Michaela was showering. I will remember Stephen, our kind black jack dealer. I will remember the woman with the vulgar language. I will remember the man who approached us, and asked if I had cancer, and then did something so special for me. I’ll remember the folks who thought Michaela and I were sisters, and I will remember the guys, who I thought were making fun of my bald head,……Oops, I better stop. I’ve said too much.
Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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Novartis takes fight to Pfizer's Ibrance with new ... - https://goo.gl/MqSEDH - #Fight, #Ibrance, #Novartis, #Nutrition, #Pfizer039S, #Takes
Novartis takes fight to Pfizer's Ibrance with new Kisqa... - https://wp.me/p8XyML-b0H - #Fight, #Ibrance, #Kisqa, #Novartis, #Pfizers, #Takes
Novartis takes fight to Pfizer’s Ibrance with new Kisqali data ZURICH (Reuters) - New data from Novartis’s breast cancer drug Kisqali underscored its effectiveness in pre-menopausal women, the Swiss drugmaker said, amid efforts to muscle in on turf dominated by rival Pfizer’s Ibrance.
