#growth factor

Pregnant Pause

These beautiful balls of cells are mouse embryos in culture, about four days after fertilisation. If transferred to a mother, it would take approximately 16 more days for them to develop and be born. If kept in culture, they would die in a day or two. That is, unless they hibernate. Indeed, scientists have recently discovered – quite by accident – that they can put cultured mouse embryos into suspended animation for up to four weeks. The researchers had been studying the effects of growth factor inhibition in mouse embryos, but had not expected development to simply pause, nor for it to restart once the inhibitor was removed. But restart it did, and the reanimated embryos, transferred to a mother, went on to develop as normal. Human embryos also deteriorate rapidly in culture. It’s therefore hoped that this serendipitous discovery might translate into ways to improve embryo viability for assisted reproduction in people.

Written by Ruth Williams

Image courtesy of the Ramalho-Santos lab, University of California, San Francisco

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences and Diabetes Center, University of California San Francisco, San Francisco, CA, USA

Image copyright held by original authors

Research published in Nature, November 2016

Not all companies experience growth that is sustainable. Some are backed by strong fundamentals, others by hype. While fast growth can be impressive, it can also be misleading. Quality is the foundation that helps growth endure, and it’s sustainable, quality-driven growth that helps build resilient portfolios.

Summary 

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Breast cancer affects about 10% of women in their lifetime and is a serious medical and social burden. Fewer treatment options are available for breast cancers that lack estrogen receptors and therefore do not respond to hormone therapy. Breast tumors that lack not only ER-alpha, but also the EGFR tyrosine kinase receptor and the progesterone receptor, are particularly difficult to treat. They…

Global Nerve Growth Factor (NGF) Market

was valued $XX Mn in 2019 and is expected to reach $XX Mn by 2026, at a CAGR of XX% during forecast period.

Global Nerve Growth Factor (NGF) Market Overview:

Nerve growth factor (NGF) is a neurotrophic protein, which is primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons.It is known to play a critical protective role in the development and survival of sympathetic, sensory and forebrain cholinergic neurons.

Global Nerve Growth Factor (NGF) Market Dynamics:

Growing cases of various neurological disorders, corneal ulcer and other autoimmune diseases are the main factors driving the market growth. Neurological disorders like Alzheimer’s disease and other diseases like a corneal ulcer, various autoimmune diseases present globally are responsible for damaging the tissue of the immune system. This factor primarily drives the Nerve Growth Factor market. Alzheimer's is most prevalent in the US, where approximately 5.5 million people are affected, and the prevalence worldwide is estimated to be as high as 24 million. Along with this, increased government funding, and ongoing research studies for the development of novel treatments using NGF for the treatment of various diseases will also boost the market growth. Another advantage of NGF such as it controls the regulation of the nervous system in embryos and regulates the growth, function & repair of neurons in adults, and nerve cell recovery after surgical or chemical injuries helps in stimulating the growth of the market. The report has profiled fifteen key players in the market from different regions. However, report has considered all market leaders, followers and new entrants with investors while analyzing the market and estimation the size of the same. Increasing R&D activities in each region are different and focus is given on the regional impact on the cost, availability of advanced technology are analyzed and report has come up with recommendations for future hot spot in APAC region.

Global Nerve Growth Factor (NGF) Market Segment Analysis:

The global Nerve Growth Factor Market is segmented on the basis of Type, Application and End-Users. Based on Application, the nerve growth factor market segmented into neurodegenerative disorders, spinal cord injuries, tissue healing, and autoimmune diseases. Neurodegenerative disorders segment is expected to dominate the market owing to numerous studies which have shown that NGF contributes to the survival and regeneration of neurons during aging and in age-related diseases such as Alzheimer’s.

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Global Nerve Growth Factor (NGF) Market Regional Insights:

North America is expected to account for highest market share during forecast period. The presence of advanced technology and favourable reimbursement policies offered by the government encourages the growth of the market in the region. Besides this, the high prevalence of the population suffering from neurodegenerative disorders, ongoing R&D activities for novel treatment development, and high healthcare expenditure contribute to the market growth. Europe is considered the second-largest market for nerve growth factor due to strategic collaboration between academic research institute and pharmaceutical giants to develop new drugs. The report also helps in understanding Global Nerve Growth Factor (NGF) Market dynamics, structure by analyzing the market segments and project the Global Nerve Growth Factor (NGF) Market size. Clear representation of competitive analysis of key players by product, price, financial position, product portfolio, growth strategies, and regional presence in the Global Nerve Growth Factor (NGF) Market make the report investor’s guide.

Global Nerve Growth Factor (NGF) Market Scope: Inquire before buying

Global Nerve Growth Factor (NGF) Market, by Region:

• North America • Europe • South America • MEA • APAC

Global Nerve Growth Factor (NGF) Market Key players:

Rotten to the bone: how a growth factor leads the marrow to drying up its normal stems

Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease’s high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) stem and progenitor cells (HSPC). Although AML makes up only about 1% of all cancers, it is the second most common type of leukemia diagnosed, according to the American…

On the role of prolactin in breast cancer: hormones, receptors and mediators on the main board

Prolactin, signaling and the mammary gland The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy. Prolactin (PRL) is a polypeptide hormone produced primarily by cells known as lactotrophs, which are located in the anterior pituitary gland of all vertebrates. In humans, PRL is also produced at multiple…

Testing up 10-fold but positivity rate seen stable at 8% | India News – Times of India

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NEW DELHI: The Covid-19 positivity rate has stabilised at round 8% over the past fortnight at the same time as every day testing has elevated by nearly 10 instances as in comparison with final month. This has resulted in India crossing a complete of over three crore samples examined cumulatively. Despite the surge in testing, the growth factor in new cases(on a regular basis’s new…