Aug 9, 2020
Adhesión de agranulocitos y diapédesis
Créditos de la imagen: ProteinLounge ® - Biolegend ® 2008
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Adhesión de agranulocitos y diapédesis
Créditos de la imagen: ProteinLounge ® - Biolegend ® 2008
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Leucemia mieloide crónica
Es un trastorno clonal malignode las células madres del sistema hematopoyético caracterizado por la proliferación o acumulación anormal de granulocitos inmaduros.
Se caracteriza por una fase crónica que dura meses hasta años, pudiendo ser asintomática. Seguida por una fase mieloproliferativa acelerada con inadecuada respuesta a tratamiento, empeorando el proceso anémico con trombocitopenia. Hasta llegar a la fase terminal caracterizada por un numero elevado de células blasticas y numerosas complicaciones por insuficiencia de la medula ósea (septicemia, hemorragias)