#fda 2025

Sevabertinib CAS 2521285-05-0 MF C24H25ClN4O5, 484.9 g/mol 3-(3-chloro-2-methoxyanilino)-2-[3-[[(2S)-1,4-dioxan-2-yl]methoxy]-4-pyridinyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one 11/19/2025, FDA 2025, APPROVALS 2025, Hyrnuo, 2A7VPM5RWH, BAY-2927088, BAY 2927088 To treat locally advanced or metastatic non-squamous non-small cell lung cancer with tumors that have activating HER2 tyrosine…

Ziftomenib CAS 2134675-36-6 4MOD1F4ENC, KO 539 717.9 g/mol, C33H42F3N9O2S2 APPROVALS 2025, FDA 2025, 11/13/2025, Komzifti 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1-[(2S)-2-(4-methylsulfonylpiperazin-1-yl)propyl]indole-2-carbonitrile To treat adults with relapsed or refractory acute myeloid leukemia with a susceptible…

Elinzanetant CAS 929046-33-3 MW 668.6 g/mol MF C33H35F7N4O3 N-[6-[(7S,9aS)-7-(hydroxymethyl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)-3-pyridinyl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide FDA 10/24/2025, Lynkuet, To treat moderate-to-severe vasomotor symptoms due to menopause BAY-3427080; GSK-1144814; NT-814,…

Remibrutinib CAS 1787294-07-8 N-[3-[6-amino-5-[2-[methyl(prop-2-enoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide MW 507.5 g/mol, MF C27H27F2N5O3 LOU064 NVP-LOU064-NXA LOU064-NXA I7MVZ8HDNU WHO 11062 APPROVALS 2025, FDA 2025, 9/30/2025, To treat chronic spontaneous urticaria in adults who remain symptomatic despite H1 antihistamine…

Imlunestrant CAS 2408840-26-4 as tosylate: 2408840-41-3 (5R)-5-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl]-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol (5r)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5h-(1)benzopyrano(4,3-c)quinolin-2-ol 5h-(1)benzopyrano(4,3-c)quinolin-2-ol,…

Donidalorsen CAS 2304692-48-4 분자량 Mw8672.64화학식MfC296H435N83O151P20S15 ISIS 721744, ISIS-721744 FDA 8/21/2025, Dawnzera, To prevent attacks of hereditary angioedema DNA,…

Dordaviprone WeightAverage: 386.499Monoisotopic: 386.210661473 Chemical FormulaC24H26N4O TIC10 CAS 1616632-77-9 Dordaviprone ONC201 ONC 201 9U35A31JAI NSC-350625 11-benzyl-7-[(2-methylphenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one Product Ingredients  IngredientUNIICASInChI KeyDordaviprone dihydrochloride53VG71J90J1638178-82-1Not…

Zongertinib CAS No. : 2728667-27-2, BI-1810631, BI1810631 Molecular Weight535.60FormulaC29H29N9O2 FDA 8/8/2025, Hernexeos, To treat adults with unresectable or metastatic non-squamous non-small cell lung cancer whose tumors have HER2 tyrosine kinase domain activating mutations, as detected by an FDA-approved test, and who have received prior systemic…