Empty vegan HPMC capsule is the best choice for herbal ingredients
Capsule shells are normally divided into empty hard capsule and softgel capsule. We mainly talk about empty hard capsule today. Empty hard capsules are composed by two parts: cap and body. If classified by raw material, the empty capsule includes gelatin empty capsule and vegetable empty capsule(normally HPMC). Now, let's make a comparison between these two kinds of empty capsules.
1, Raw material: The main ingredient of gelatin empty capsule is the high quality medicinal gelatin that is sourced from collagen in the skins and bones of animals, which is hydrolyzed from animal connective tissue or epidermal tissue, whereas the main ingredient of HPMC capsule is hydroxypropyl methylcellulose, which is hydrolyzed from plant after etherification. The increasing use of vegetable capsule globally attributes to the religious belief(Judaism, Islam), dietary habits(veggie), the demand for green and nature and the precaution of diseases(mad cow disease) that are caused by animals.
2, Chemical stability: There are residue, cross-linking, delayed disintegration and electrostatic interactions problems in Gelatin, whereas HPMC enjoys a stable chemistry, no cross-linking, no disintegration problems and non-electrostatic action.
3, Moisture Content: As we know, too many moisture content has a tremendous impact on the stability to moisture-sensitive drugs. The moisture content of gelatin capsule is 13-15% in the temperature of 20-25 degree Celsius(RH at 40%-60%), but for HPMC capsule, the moisture content is only round 4%-6%. Besides, the gelatin capsule shell will become brittle when the moisture content is below 10%, while HPMC capsule shell will not be friable even the moisture content is at 1%.
4, Preservatives: The main ingredient of gelatin capsule is protein, a kind of ingredient that is easy to breed bacteria and microorganisms, which will be needed to add some preservatives and bacteriostasis in the production process and sterilize by ethylene oxide in order to maintain the stable parameter of microorganism of capsule shell. However, there is no need any preservatives in the production process for HPMC capsule and no need to be sterilized by ethylene oxide.
In summary, HPMC empty capsules are better than gelatin capsule in many aspects such as chemical stability, storage environment and shipping conditions as well as water content with low carbon, degradable, eco-friendly and sustainable development, no any religious belief restriction, ideal for Chinese herbal medicines, dietary supplements, liquid probiotics, powder and cosmetics.
About us:
A leading FDA-grade vegetable empty capsule manufacturer in China with established R&D team for over decades. Our capsules boast a high filling rate of 99.8%, customized low moisture content, meet GMP standards.
Product includes: empty vegetable capsule, acid resistant empty capsule, liquid filled empty capsule, delayed release veggie capsule, Colored HPMC vegetable empty capsules, Pullulan vegetable empty capsules, hydroxypropyl starch vegetarian capsule, printed vegetable empty capsule, transparent hollow capsule, Kosher&Halal HPMC vegetable empty capsule.
Contact: +8613560169928(Joyce Zhang)
www.jiucapsule.com email: [email protected]
Guangzhou Jiuzhou Capsule Bio-Pharmaceutical Co., LTD
