In a Quality Control (QC) laboratory, the margin for error is virtually zero. Whether you are testing the purity of a new pharmaceutical compound, monitoring fermentation in the wine industry, or ensuring food safety, your data must be defensible and reproducible. In 2026, the Microlit E-Burette has emerged as an indispensable tool for QC professionals who need to replace manual variability with digital certainty.

1. Eliminating Subjectivity in Titration

The biggest threat to a QC lab’s integrity is the "human factor." Traditional titration relies on a technician’s ability to judge a color change and manually control a stopcock. The e-burette removes this subjectivity with its high-precision, motor-controlled piston. By delivering titrants smoothly and consistently, it ensures that every titration is performed with the same level of mechanical accuracy, regardless of the operator.

2. Achieving the Perfect Endpoint

Missing an endpoint can mean the difference between a batch being approved or scrapped. The Microlit E-Burette features three calibrated pre-set speeds, including a specialized dropwise mode. This allows QC technicians to dispense exactly 0.01 ml per drop as they approach the equivalence point. This level of granular control is nearly impossible to achieve with manual stopcocks, significantly reducing the risk of overshooting.

3. Traceability and Data Integrity

Modern QC labs must adhere to strict regulatory standards like GLP and ISO 8655. The e-burette is built for this environment. It features:

Internal Memory: Stores up to 20 titration results with time and date stamps.

Connectivity: Allows for direct data transfer to a computer, eliminating manual transcription errors.

21 CFR Software: Optional software that complies with USFDA 21 CFR Part 11 for enhanced data security and multi-step authentication.

4. Maximizing Reagent Efficiency

Expensive reagents are a significant lab overhead. The e-burette includes a recirculation valve that prevents reagent loss during the purging process by redirecting it back into the bottle. This ensures a bubble-free dispensing path without wasting a single drop of titrant.

As laboratory research and scientific work continue to evolve, the need for precise and efficient liquid handling instruments becomes even more vital. At Microlit, we take pride in designing and delivering high-quality liquid handling instruments that cater to the ever-demanding needs of modern laboratories. In 2024, our advanced products continue to set the benchmark for accuracy, ease of use, and innovative design. Here, we explore the top Microlit models that are redefining liquid handling practices this year.

1. Microlit Beatus Series – Excellence in Electronic Pipetting

The Microlit Beatus Series has become a standout in the electronic pipette category, offering unmatched convenience and performance. Ideal for high-throughput laboratories, these electronic pipettes feature an intuitive interface that allows users to switch seamlessly between modes, such as multi-dispensing and reverse pipetting. The programmable functions ensure accuracy and reduce user fatigue, making them essential for busy lab environments.

Key Features:

Effortless multi-dispensing for repetitive tasks

User-friendly digital interface

High precision with adjustable speed control

2. Microlit E-Burette – Redefining Titration Precision

The Microlit E-Burette is perfect for laboratories that require precise titration. This motorized burette combines modern technology with user-centric design to simplify the process of titration while enhancing accuracy. With an easy-to-read digital display and smooth motorized control, the E-Burette helps researchers achieve consistent results without the errors associated with manual titration.

Key Features:

Digital display for easy monitoring

Precision motorized dispensing

Easy handling and adaptable to various titration tasks

3. Microlit RBO Micropipettes – Reliable Everyday Pipetting

The Microlit RBO Micropipettes are trusted by scientists for their robust design and seamless performance. Available in both adjustable and fixed volume variants, these micropipettes are known for their soft plunger movement, lightweight build, and high accuracy. They are ideal for routine lab tasks where dependable performance is a must.

Key Features:

Available in both single-channel and multi-channel formats

Ergonomic design for comfortable use

Accurate and reliable performance for various volumes

4. Microlit Lentus Bottle Top Dispensers – Safe and Efficient Dispensing

When it comes to handling reagents directly from bottles, the Microlit Lentus Bottle Top Dispensers are the perfect choice. These dispensers feature a recirculation valve that minimizes waste and ensures precise dispensing with every use. Built with chemical-resistant materials, they are suited for handling both standard and aggressive liquids safely.

Key Features:

Recirculation valve to prevent liquid waste

Chemically resistant construction

Smooth and accurate dispensing with adjustable volume control

5. Microlit Scitus Bottle Top Dispensers – Precision Redefined

The Microlit Scitus series offers high accuracy for laboratories that need precision in liquid dispensing. With advanced pipette calibration options and a reliable build, these dispensers are perfect for rigorous lab protocols that demand exact measurements. The Scitus models come with a smooth piston movement for precise and effortless operation. 

Key Features:

Advanced calibration for precise results

Easy-to-operate design with smooth movement

Suitable for a variety of liquid handling applications

6. Microlit ULTIMUS Bottle Top Dispensers – Versatility in Action

The Microlit ULTIMUS series takes versatility and ease of use to new heights. Designed with user safety and convenience in mind, these dispensers come equipped with additional safety valves and adaptable nozzle features. They are engineered to handle a range of liquids efficiently, making them a versatile tool in any laboratory automation.

Key Features:

Safety valve for secure use

Adaptable nozzle for various container sizes

Reliable and consistent dispensing performance

Conclusion

Microlit is proud to be at the forefront of liquid handling technology, offering a range of products that cater to different laboratory needs. Whether you are pipetting, titrating, or dispensing, our instruments are designed to provide precision, reliability, and ease of use. From the sophisticated Microlit Beatus Series and versatile RBO Micropipettes to the reliable Lentus and Scitus bottle top dispensers, we have a solution for every liquid handling requirement in 2024.

Enzyme-linked immunosorbent assays (ELISA) and other immunoassays are essential tools in laboratories for detecting and quantifying biological molecules such as proteins, antibodies, and hormones. These assays are widely used in diagnostics, research, and pharmaceutical industries due to their sensitivity and specificity. However, for these tests to deliver accurate and reproducible results, precise liquid handling is crucial.

In this blog, we’ll explore how liquid handling instruments play a key role in ELISA and other immunoassays, and what tools can enhance the efficiency and accuracy of these assays. 

Understanding the Role of Liquid Handling in ELISA and Immunoassays

ELISA and immunoassays typically involve multiple steps, such as adding reagents, washing, and detecting signals from the sample. Each of these steps requires precise dispensing of liquids to ensure proper binding and reaction between molecules. Even small inconsistencies in pipetting can lead to errors in results, compromising the reliability of the data. 

Here are some steps where precise liquid handling is vital:

Sample Dispensing: Accurate measurement of the sample to ensure consistent concentration across wells. 

Reagent Addition: Reagents, such as antibodies or substrates, must be added uniformly for reproducibility. 

Washing: Thorough washing of wells to remove unbound material and minimize background noise. 

Substrate Addition: Ensuring equal amounts of substrate to each well for uniform colorimetric or fluorescent signals. 

Liquid Handling Solutions for ELISA and Immunoassays

Let’s take a look at some advanced liquid handling solutions that help labs achieve high-quality ELISA and immunoassay results. 

1. Micropipettes

Micropipettes are essential tools for handling small volumes of liquid in immunoassays. Both manual and automated micropipettes are widely used for dispensing reagents and samples in ELISA. Key factors when selecting micropipettes for immunoassays include accuracy, precision, and ergonomic design.

Microlit NERO Micropipettes: Known for its ergonomic design and superior accuracy, the NERO range includes both single-channel and multi-channel micropipettes. Multi-channel options are particularly useful in ELISA, allowing multiple wells to be filled simultaneously, speeding up the process and reducing variability. 

2. Electronic Dispensers

Electronic dispensers simplify repetitive pipetting tasks and reduce the chances of human error. They are useful for adding reagents in fixed or variable volumes during different stages of ELISA and immunoassays. 

Microlit E-BURETTE: This E-Burette is designed to dispense precise amounts of reagents effortlessly. It eliminates user fatigue and enhances consistency, which is critical when handling large numbers of samples in immunoassays.

3. Bottle Top Dispensers

For laboratories dealing with multiple reagents in large volumes, bottle top dispensers provide an efficient solution. These dispensers allow easy, accurate, and contamination-free transfer of reagents directly from the bottle.

Microlit BEATUS: A bottle top dispenser with excellent chemical compatibility and precision, BEATUS ensures that reagents are safely and accurately dispensed, reducing the risk of cross-contamination in ELISA and immunoassays.

4. Automated Liquid Handling Systems

Automation is transforming laboratories by increasing throughput and minimizing manual intervention. Automated liquid handling systems can perform complex pipetting tasks, including sample preparation, washing, and reagent addition, with precision and speed.

While high-throughput labs benefit greatly from automation, smaller labs can still achieve consistency by using electronic pipettes and semi-automated dispensers for immunoassays.

Best Practices for Liquid Handling in ELISA and Immunoassays

To make the most of liquid handling solutions and improve the accuracy of immunoassays, labs can follow these best practices:

Regular Calibration: Ensure that pipettes and dispensers are regularly calibrated to maintain accuracy.

Use Multi-Channel Pipettes: Multi-channel pipettes can significantly reduce variability between wells, particularly when adding samples or reagents in ELISA plates.

Minimize Air Bubbles: When aspirating and dispensing, be mindful of air bubbles as they can cause inconsistencies in volume and affect results.

Avoid Touching the Sidewalls: During pipetting, avoid touching the sides of wells as this can lead to inaccurate volumes and cross-contamination. 

Conclusion

Liquid handling plays a fundamental role in ensuring the success of ELISA and other immunoassays. By using precise and reliable tools like micropipettes, electronic dispensers, and bottle top dispensers, labs can improve the accuracy and reproducibility of their assays.

When it comes to selecting the most durable electronic pipette, Microlit E-Burette stands out as an exceptional choice in the market. Known for its robustness, precision, and user-friendly features, this electronic pipette is designed to meet the rigorous demands of modern laboratories. Here is a closer look at what makes the Microlit’s  E-Burette the most durable electronic pipette available:

1. Construction and Materials

The E-Burette is constructed from high-quality materials that ensure long-lasting performance. Its body is made from chemically resistant plastic and metal components, which protect it from corrosion and wear. The use of durable materials means that the pipette can withstand frequent use and harsh laboratory conditions without compromising its functionality. 

2. Advanced Technology

This electronic pipette incorporates advanced laboratory technology that enhances its durability. It features an electronic control system that reduces manual strain and ensures consistent and accurate dispensing of liquids. The precision motor used in the E-Burette is designed for longevity, providing reliable performance over an extended period.

3. User-Friendly Design

The ergonomic design of the E-Burette by Microlit adds to its durability by minimizing user fatigue and preventing errors that can lead to damage. Its intuitive interface and easy-to-read display make it simple to operate, reducing the risk of mishandling. The lightweight design also ensures that users can handle it comfortably for extended periods, further contributing to its long lifespan.

4. Versatility and Adaptability

The E-Burette is compatible with a wide range of liquid handling applications, making it a versatile tool in any laboratory setting. Its adaptability to various tasks without needing frequent recalibration or adjustments speaks to its robust construction and dependable performance.

5. Maintenance and Calibration

Regular maintenance and calibration are crucial for the longevity of any electronic pipette. The Microlit E-Burette is designed for easy maintenance, with components that can be easily cleaned and replaced if necessary. Its calibration process is straightforward, ensuring that it remains accurate and reliable with minimal effort.

6. Manufacturer’s Warranty and Support

We offer excellent customer support and a comprehensive warranty for the E-Burette, ensuring that any issues are promptly addressed. This commitment to customer satisfaction further enhances the pipette’s durability, as users can rely on the manufacturer for repairs and replacements when needed.

Conclusion