During pregnancy, there is a possibility that the chromosomes of developing featus might not form correctly, resulting in improper development of the baby. Such issue arises when there is an abnormal number of chromosomes. A screening method called the double marker test, or dual marker test, helps evaluate the likelihood of certain inherited conditions.

The double marker test is widely used to assess the chances of genetic variations. It helps in identifying the risk of conditions such as Down syndrome, Patau syndrome, and Edward syndrome. This test is part of early prenatal screening and is typically performed during the first trimester, within the first three months of pregnancy.

Certain couples may have a higher probability of having a child with birth defects. This risk increases with factors such as advanced maternal age, a previous history of congenital issues, diabetes, or the use of specific medications during pregnancy. Screening tests like the double marker test allow early assessment of such risks. It is also a key component of first trimester screening and helps detect possible chromosomal abnormalities, which may otherwise lead to developmental concerns or health complications after birth.

If you are looking for the best diagnostic and pathology centres in your vicinity, you can do an online search with keywords double marker test near me.

What is the procedure?

It is a simple blood test that requires drawing a blood sample from a vein in the arm. It measures two important markers:

Free Beta hCG (human chorionic gonadotrophin)

PAPP-A (pregnancy-associated plasma protein A)

Higher levels of Free Beta hCG may indicate an increased risk of conditions such as Down syndrome or Trisomy 18. Lower levels of PAPP-A are also associated with a higher likelihood of Down syndrome. Trisomy refers to a condition where there is an extra chromosome present.

No fasting is required before the test. Variations in the levels of these markers can suggest a possible chromosomal imbalance.

In addition to the blood test, a nuchal translucency (NT) scan is usually advised. This ultrasound measures the fluid-filled space at the back of the baby’s neck and provides additional information for risk assessment.

The double marker test price may vary depending on the diagnostic center and location.

When is the test recommended?

The double marker test is often advised as a routine screening, but it becomes especially important in the following situations:

• Women in their 35 and above

• Those who have a family history of genetic or congenital disorders

• Presence of diabetes or a strong family history of metabolic conditions

What is the purpose of the test?

This test is designed to assess the risk of chromosomal abnormalities in the developing baby. It does not provide a definitive diagnosis but indicates whether further testing may be required.

A double marker test is an important test done in the first trimester of pregnancy to determine the healthy development of the foetus. The test helps pregnant women to determine any chromosomal abnormalities in the foetus. 

Double marker test, also known as the dual marker test, is a prenatal screening test that is performed during pregnancy to determine the risk of chromosomal abnormalities in the fetus. This test is usually recommended for women who are at a higher risk of having a baby with Down syndrome or other chromosomal abnormalities.

It is done to check for the levels of two specific hormones, hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein A), in the mother's blood. The levels of these hormones can provide information about the risk of certain chromosomal abnormalities in the fetus, such as Down syndrome, Edward's syndrome, and Patau syndrome. If you live in Delhi-NCR, you can find out Double Marker test by contacting your nearest diagnostic and pathology lab.

The test is recommended for pregnant women who are 35 years or older, have a family history of chromosomal abnormalities, have a previous child with a chromosomal abnormality, or have abnormalities detected during an ultrasound. It can be done between 10 and 14 weeks of pregnancy and is a non-invasive test that does not pose any risk to the mother or the fetus. You can also find out ‘Double Marker test price’ by doing an online search.