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Strategic Guide: Managing OOS Investigations in Pharmaceutical Quality Control with real example
An Out of Specification (OOS) investigation is a critical regulatory requirement in the pharmaceutical industry. When an analytical result falls outside the established specifications or acceptance criteria (defined in pharmacopoeias, drug applications, or internal specifications), it cannot simply be ignored. The primary regulatory frameworks governing this process are the FDA Guidance for…
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HPLC columns classification
HPLC column HPLC columns are classified in the United States Pharmacopeia (USP) under the “L” designation system, with each type assigned a specific USP code (e.g., L1, L3, L7). The main USP chapter that governs chromatography, including HPLC columns, is USP Chromatography, which provides detailed guidance on column selection, performance, and validation. 📖 USP Chapter Reference USP…
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Which pharma Aqueous product give bring more water loss 60℅Rh OR 90℅ Rh
It’s 60℅ Rh because (100 – 60 = 40 ℅ loss water (100-90 = 10 ℅ loss water Here 100 is in side containers water Inside container concentration might be different but, it’s water remain 100 ℅
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