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Diphencyprone (DPCP) is a topical treatment used for patients with alopecia areata. After an initial application dose of 2%, patients (or their family member, spouse, etc) apply the medication at home on a weekly basis - provided they have received appropriate training from our office. Training is important as DPCP can cause serious rashes and blisters to other parts of the body if not properly applied. Nitrile gloves are recommended by the individual applying DPCP to limit his or her exposure. We prefer this over latex or vinyl gloves. #aa #alopecia #dpcp #alopeciaawareness #diphencyprone

Diphencyprone (DPCP) is a topical treatment widely used for adults and children with more advanced stages of alopecia areata - especially those individuals who have lost greater than 50 % of their hair. The treatment is typically applied weekly. It had been studied for well over 30 years. DPCP can be effective in many patients and is much more effective for patients with localized AA than in those with complete scalp hair loss (alopecia totalis and universalis). In this post, I'd like to focus on options for patients who are responding "partially" to treatment with DPCP but not fully. What can be done? There are several options including 1) increasing DPCP concentrations slowly upwards of 6-8% as tolerated by the patient 2) adding minoxidil daily to the treatment plan 3) using anthralin with DPCP or 4) using imiquimod together with DPCP, 5) adding tretinoin gel prior to DPCP application to make the DPCP more irritating and 6) applying DPCP twice weekly rather than once weekly. These are 6 options that can improve outcomes for patients that aren't fully responding to the DPCP. They should be carried out in conjunction with a physician knowledgable about the use and application of DPCP. #dpcp #alopecia #diphencyprone #anthralin #minoxidil #alopeciaareata #rogaine #imiquimod

Alopecia areata has many forms. These forms go by names such as monolocularis, multilicularis, reticular, ophiasis, sisaipho, totalis, universalis, perinevoid, barbae, etc Alopecia areata ophiasis is a form of alopecia areata affecting predominantly the back and sides of the scalp. This form is important to recognize because it may be more challenging to treat. Nevertheless, some patients respond to steroid injections, topical steroids, anthralin, diphencyprone, platelet rich plasma, methotrexate, cyclosporine, tofacitinib, or prednisone. #alopecia #prednisone #tofacitinib #methotrexate #alopeciaareata #diphencyprone