The essential Proteins for Covid-19 Research, Diagnosis and Medication COVID-19 is (most likely) the year defining topic of 2020, even beyond life sciences and medicine. Trying to find a working treatment for the disease is crucial and Cube Biotech @cubebiotech contributes to the global research. -SARS-CoV2 infection scheme: First the surface protein of the Coronavirus called SPIKE is processed through a proteolytic cleavage by the cell surface serine protease TMPRSS2. This brings the SPIKE protein into its active state in which it can interact with the cell surface receptor and metallocarboxypeptidase ACE2. This subsequently leads to the fusion on the virus membrane with the cell membrane similar to a vesicular import. This way the infection viral RNA genome enters the cell. -SPIKE: SARS-CoV-2's key into our cells. -ACE2 and TMPRSS2 - COVID-19's involuntary helpers ACE2 “receptor,” the protein provides the entry point for the coronavirus to hook into and infect a wide range of human cells. TMPRSS2 Activates the Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response -Cube Biotech supports the COVID-19 Researchers across the globe by providing the High Quality and the Best in Class Products for your Research requirement. As leading experts in the field of membrane protein stabilization and solubilization it is a logical step for us to provide you with aliquots of pure & full length ACE2 , SPIKE and TMPRSS2 protein in MSP and synthetic nanodiscs. SPIKE - Full-Length & Complete by Cube Biotech Right now, the lifescience market is flooded with coronavirus protein offers. But our own market analysis shows that only fragments or single domains can be obtained from other competitors. As experts for membrane proteins we successfully stabilized the full-lenght trimeric version of SARS-CoV-2's SPIKE protein. Cube Biotech is the only company that offers the full-length trimeric & active version. Therefore Cube Biotech comes the closest to the native SPIKE proteins structure. #cubebiotech #biotech #biotechnology #protein #proteins #molecularbiology #molbio #lab #laboratory #labequipment #biotech #lifescience https://www.instagram.com/p/CIXkMRJDxmv/?igshid=1q7yt3651y4k0
