#corebodytemperature

Labmate Rectal Thermometer measures core body temperature during clinical, veterinary, and laboratory animal monitoring procedures.

Used as a digital rectal thermometer, it supports accurate temperature measurement for routine examinations, physiological assessment, and diagnostic testing.

Light effects on circadian rhythm (circadian rhythm is a natural, internal process that regulates the sleep-wake cycle and repeats every 24 hours) and sleep mask It can refer to any biological process that displays an endogenous, entrainable oscillation of about 24 hours. These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in plants, animals, fungi, and cyanobacteria. Light effects on circadian rhythm Light effects on circadian rhythm are the effects that light has on circadian rhythm, sleep, mood, Life.

Light effects on circadian rhythm and sleep mask Most animals and other organisms have "built-in clocks" in their brains that regulate the timing of biological processes and daily behavior. These "clocks" are known as circadian rhythms. They allow maintenance of these processes and behaviors relative to the 24-hour day/night cycle in nature. Although these rhythms are maintained by the individual organisms, their length does vary somewhat individually. Therefore, they must, either continually or repeatedly, be reset to synchronize with nature's cycle. In order to maintain synchronization to 24 hours, external factors must play some role. The human circadian rhythm occurs typically in accordance with nature's cycle. The average activity rhythm cycle is 24.18 hours in adulthood but is shortened as age increases. One of the various factors that influence this entrainment is light exposure to the eyes. When an organism is exposed to a specific wavelength of light stimulus at certain times throughout the day, the hormone melatonin is suppressed, or prevented from being secreted by the pineal gland. More: The Energy of Space, Wiki, Research on IUMAB Library Effects of light on human circadian rhythms, sleep and mood Abstract Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern. Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is entrained to the 24-hour solar day via a pathway from the retina and synchronises our internal biological rhythms. Rhythmic variations in ambient illumination impact behaviours such as rest during sleep and activity during wakefulness as well as their underlying biological processes. Rather recently, the availability of artificial light has substantially changed the light environment, especially during evening and night hours. This may increase the risk of developing circadian rhythm sleep–wake disorders (CRSWD), which are often caused by a misalignment of endogenous circadian rhythms and external light–dark cycles. While the exact relationship between the availability of artificial light and CRSWD remains to be established, nocturnal light has been shown to alter circadian rhythms and sleep in humans. On the other hand, light can also be used as an effective and noninvasive therapeutic option with little to no side effects, to improve sleep, mood and general well-being. This article reviews our current state of knowledge regarding the effects of light on circadian rhythms, sleep, and mood. Keywords Circadian rhythms, Natural light, Artificial light Depression, Light therapy  Abbreviations ADHD - Attention deficit hyperactivity disorder BLT - Bright light therapy CCT - Correlated colour temperature CIE - Commission Internationale de l’Eclairage CRSWD - Circadian rhythm sleep-wake disorders DLMO - Dim-light melatonin onset EEG - Electroencephalogram GHT - Geniculohypothalamic tract IGL - Intergeniculate leafletip RGC - Intrinsically photosensitive retinal ganglion cell LED - Light-emitting diode PRC - Phase response curve RGC - Retinal ganglion cell RHT - Retinohypothalamic tract RN - Raphe nuclei SAD - Seasonal affective disorder SCN - Suprachiasmatic nuclei SSRI - Selective serotonin reuptake inhibitor SWA - Slow wave activity UV - Ultraviolet All authors contributed equally to the manuscript. Auswirkungen von Licht auf zirkadiane Rhythmen, Schlaf und die Stimmung bei Menschen Zusammenfassung Der Mensch lebt in einer 24-Stunden-Umgebung, in der sich Licht und Dunkelheit abwechseln. Unser zirkadianer Schrittmacher in den suprachiasmatischen Nuclei (SCN) des Hypothalamus synchronisiert unsere inneren biologischen Rhythmen mit dem Tagesverlauf des Sonnenlichts über Leitungsbahnen, die von der Netzhaut zu den SCN ziehen. Rhythmische Schwankungen in der Umgebungsbeleuchtung beeinflussen unser Verhalten, etwa den Wechsel zwischen Ruhe im Schlaf und Aktivität im Wachzustand, und dessen zugrunde liegenden biologischen Prozesse. In jüngster Zeit hat die Verfügbarkeit von künstlichem Licht die Lichtumgebung erheblich verändert, insbesondere während der Abend- und Nachtstunden. Dies kann das Risiko für die Entstehung von circadianen Schlaf-Wach-Rhythmusstörungen („circadian rhythm sleep-wake disorders“, CRSWD) erhöhen, die oft durch eine Fehlausrichtung bzw. einen Versatz zwischen endogenen tageszeitlichen Rhythmen und dem externen Hell-Dunkel-Zyklus verursacht werden. Zwar ist der genaue Zusammenhang zwischen der Verfügbarkeit von künstlichem Licht und CRSWD noch nicht geklärt, doch es hat sich gezeigt, dass nächtliches Licht den zirkadianen Rhythmus und den Schlaf beim Menschen verändert. Andererseits kann Licht auch als effektive, nichtinvasive Therapieoption mit geringen bis keinen Nebenwirkungen eingesetzt werden, um Schlaf, Stimmung und Allgemeinbefinden zu verbessern. Der vorliegende Beitrag gibt einen Überblick über den aktuellen Wissensstand hinsichtlich der Auswirkungen von Licht auf zirkadiane Rhythmen, Schlaf und Stimmung. Schlüsselwörter Zirkadiane Rhythmen, Natürliches Licht, Künstliches Licht Depression, Lichttherapie  Anatomical architecture of the circadian system The central master-clock in mammalian species, including humans, is the suprachiasmatic nuclei (SCN), a paired structure in the hypothalamus with a volume just about 0.25 mm3 per nucleus (e.g. ). Within the mammalian SCN, a molecular oscillator keeps the clock oscillating at its normal pace. The basis of this oscillator is two interconnected molecular feedback loops of clock gene expression, a detailed description of which is beyond the scope of this review though (see for a detailed explanation). More https://link.springer.com/article/10.1007%2Fs11818-019-00215-x Sleep mask version of the Biointernet Mask Classic About The Biointernet Mask Sleep Mask Digital Download Sleep Now! Translighters Digital Technologies by Sergey Avdeev and Kirill Korotkov Sleep mask version of the Biointernet Mask Classic Download Sleep Now! Translighters Digital Technologies by Sergey Avdeev and Kirill Korotkov The Biointernet Sleep Mask Digital – digital sleep mask version of the Biointernet Mask Classic Shop now The Biointernet Sleep Mask Digital – digital sleep mask version of the Biointernet Mask 9 MB Serial number: 5432 Translighters Digital Technologies – Images, videos, text, web, Social Media and other files with Translighters functions Create Your Own Night Dream Today!

The Biointernet Mask Light effects on circadian rhythm and sleep mask Systematic review of light exposure impact on human circadian rhythm ABSTRACT Light is necessary for life, and artificial light improves visual performance and safety, but there is an increasing concern of the potential health and environmental impacts of light. Findings from a number of studies suggest that mistimed light exposure disrupts the circadian rhythm in humans, potentially causing further health impacts. However, a variety of methods has been applied in individual experimental studies of light-induced circadian impacts, including definition of light exposure and outcomes. Thus, a systematic review is needed to synthesize the results. In addition, a review of the scientific evidence on the impacts of light on circadian rhythm is needed for developing an evaluation method of light pollution, i.e., the negative impacts of artificial light, in life cycle assessment (LCA). The current LCA practice does not have a method to evaluate the light pollution, neither in terms of human health nor the ecological impacts. The systematic literature survey was conducted by searching for two concepts: light and circadian rhythm. The circadian rhythm was searched with additional terms of melatonin and rapid-eye-movement (REM) sleep. The literature search resulted to 128 articles which were subjected to a data collection and analysis. Melatonin secretion was studied in 122 articles and REM sleep in 13 articles. The reports on melatonin secretion were divided into studies with specific light exposure (101 reports), usually in a controlled laboratory environment, and studies of prevailing light conditions typical at home or work environments (21 studies). Studies were generally conducted on adults in their twenties or thirties, but only very few studies experimented on children and elderly adults. Surprisingly many studies were conducted with a small sample size: 39 out of 128 studies were conducted with 10 or less subjects. The quality criteria of studies for more profound synthesis were a minimum sample size of 20 subjects and providing details of the light exposure (spectrum or wavelength; illuminance, irradiance or photon density). This resulted to 13 qualified studies on melatonin and 2 studies on REM sleep. Further analysis of these 15 reports indicated that a two-hour exposure to blue light (460 nm) in the evening suppresses melatonin, the maximum melatonin-suppressing effect being achieved at the shortest wavelengths (424 nm, violet). The melatonin concentration recovered rather rapidly, within 15 min from cessation of the exposure, suggesting a short-term or simultaneous impact of light exposure on the melatonin secretion. Melatonin secretion and suppression were reduced with age, but the light-induced circadian phase advance was not impaired with age. Light exposure in the evening, at night and in the morning affected the circadian phase of melatonin levels. In addition, even the longest wavelengths (631 nm, red) and intermittent light exposures induced circadian resetting responses, and exposure to low light levels (5–10 lux) at night when sleeping with eyes closed induced a circadian response. The review enables further development of an evaluation method of light pollution in LCA regarding the light-induced impacts on human circadian system. KEYWORDS: Light, human health, melatonin, REM sleep, health, circadian rhythm Introduction Artificial light is a necessity in the modern societies. It provides illumination when natural light is not available enabling a multitude of functions after dark. It is intended to improve the visual performance and visibility in indoor and outdoor environments, thus improving safety and comfort of humans. In addition, artificial light may serve as a source for relaxation and beauty, and to improve alertness and productivity. More: https://www.tandfonline.com/doi/full/10.1080/07420528.2018.1527773 The human circadian system in normal and disordered sleep. Abstract The human circadian system regulates rhythmicity in the human body and establishes normal sleep and wake phases. The suprachiasmatic nuclei (SCN), located in the hypothalamus above the optic chiasm, make up the human pacemaker known as the circadian or biological clock, but other essential parts of the circadian system include the pineal gland, retina, and retinohypothalamic tract. The importance of light in resetting the intrinsic human circadian cycle, the intrinsic period of which is slightly longer than 24 hours, ensures that the human cycle will stay entrained to the earth's 24-hour daily cycle. Within the SCN neurons, circadian rhythmicity is generated by the regular transcription of proteins. Since the circadian system is the foundation of the sleep-wake cycle, disorders and abnormalities in sleep are often connected with disorders or abnormalities in the circadian system. Circadian rhythm sleep disorders, such as jet lag syndrome and shift work sleep disorder, are those specifically attributed to dysfunctions or insufficiencies in the circadian system. Taking into consideration the preeminence of the circadian clock in timing sleep, it is likely that other sleep disorders, such as insomnia, are also linked to circadian system abnormalities. More: https://www.ncbi.nlm.nih.gov/pubmed/16336035 Effect of Light on Human Circadian Physiology Synopsis The circadian system in animals and humans, being near but not exactly 24-hours in cycle length, must be reset on a daily basis in order to remain in synchrony with external environmental time. This process of entrainment is achieved in most mammals through regular exposure to light and darkness. In this chapter, we review the results of studies conducted in our laboratory and others over the past 25 years in which the effects of light on the human circadian timing system were investigated. These studies have revealed, how the timing, intensity, duration, and wavelength of light affect the human biological clock. Our most recent studies also demonstrate that there is much yet to learn about the effects of light on the human circadian timing system. Keywords: biological rhythm, core body temperature, illuminance, melatonin, phase response curve

ntroduction

Light effects on circadian rhythm (circadian rhythm is a natural, internal process that regulates the sleep-wake cycle and repeats every 24 hours) and sleep mask It can refer to any biological process that displays an endogenous, entrainable oscillation of about 24 hours. These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in plants, animals, fungi, and cyanobacteria. Light effects on circadian rhythm Light effects on circadian rhythm are the effects that light has on circadian rhythm, sleep, mood, Life.

Light effects on circadian rhythm and sleep mask Most animals and other organisms have "built-in clocks" in their brains that regulate the timing of biological processes and daily behavior. These "clocks" are known as circadian rhythms. They allow maintenance of these processes and behaviors relative to the 24-hour day/night cycle in nature. Although these rhythms are maintained by the individual organisms, their length does vary somewhat individually. Therefore, they must, either continually or repeatedly, be reset to synchronize with nature's cycle. In order to maintain synchronization to 24 hours, external factors must play some role. The human circadian rhythm occurs typically in accordance with nature's cycle. The average activity rhythm cycle is 24.18 hours in adulthood but is shortened as age increases. One of the various factors that influence this entrainment is light exposure to the eyes. When an organism is exposed to a specific wavelength of light stimulus at certain times throughout the day, the hormone melatonin is suppressed, or prevented from being secreted by the pineal gland. More: The Energy of Space, Wiki, Research on IUMAB Library Effects of light on human circadian rhythms, sleep and mood Abstract Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern. Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is entrained to the 24-hour solar day via a pathway from the retina and synchronises our internal biological rhythms. Rhythmic variations in ambient illumination impact behaviours such as rest during sleep and activity during wakefulness as well as their underlying biological processes. Rather recently, the availability of artificial light has substantially changed the light environment, especially during evening and night hours. This may increase the risk of developing circadian rhythm sleep–wake disorders (CRSWD), which are often caused by a misalignment of endogenous circadian rhythms and external light–dark cycles. While the exact relationship between the availability of artificial light and CRSWD remains to be established, nocturnal light has been shown to alter circadian rhythms and sleep in humans. On the other hand, light can also be used as an effective and noninvasive therapeutic option with little to no side effects, to improve sleep, mood and general well-being. This article reviews our current state of knowledge regarding the effects of light on circadian rhythms, sleep, and mood. Keywords Circadian rhythms, Natural light, Artificial light Depression, Light therapy  Abbreviations ADHD - Attention deficit hyperactivity disorder BLT - Bright light therapy CCT - Correlated colour temperature CIE - Commission Internationale de l’Eclairage CRSWD - Circadian rhythm sleep-wake disorders DLMO - Dim-light melatonin onset EEG - Electroencephalogram GHT - Geniculohypothalamic tract IGL - Intergeniculate leafletip RGC - Intrinsically photosensitive retinal ganglion cell LED - Light-emitting diode PRC - Phase response curve RGC - Retinal ganglion cell RHT - Retinohypothalamic tract RN - Raphe nuclei SAD - Seasonal affective disorder SCN - Suprachiasmatic nuclei SSRI - Selective serotonin reuptake inhibitor SWA - Slow wave activity UV - Ultraviolet All authors contributed equally to the manuscript. Auswirkungen von Licht auf zirkadiane Rhythmen, Schlaf und die Stimmung bei Menschen Zusammenfassung Der Mensch lebt in einer 24-Stunden-Umgebung, in der sich Licht und Dunkelheit abwechseln. Unser zirkadianer Schrittmacher in den suprachiasmatischen Nuclei (SCN) des Hypothalamus synchronisiert unsere inneren biologischen Rhythmen mit dem Tagesverlauf des Sonnenlichts über Leitungsbahnen, die von der Netzhaut zu den SCN ziehen. Rhythmische Schwankungen in der Umgebungsbeleuchtung beeinflussen unser Verhalten, etwa den Wechsel zwischen Ruhe im Schlaf und Aktivität im Wachzustand, und dessen zugrunde liegenden biologischen Prozesse. In jüngster Zeit hat die Verfügbarkeit von künstlichem Licht die Lichtumgebung erheblich verändert, insbesondere während der Abend- und Nachtstunden. Dies kann das Risiko für die Entstehung von circadianen Schlaf-Wach-Rhythmusstörungen („circadian rhythm sleep-wake disorders“, CRSWD) erhöhen, die oft durch eine Fehlausrichtung bzw. einen Versatz zwischen endogenen tageszeitlichen Rhythmen und dem externen Hell-Dunkel-Zyklus verursacht werden. Zwar ist der genaue Zusammenhang zwischen der Verfügbarkeit von künstlichem Licht und CRSWD noch nicht geklärt, doch es hat sich gezeigt, dass nächtliches Licht den zirkadianen Rhythmus und den Schlaf beim Menschen verändert. Andererseits kann Licht auch als effektive, nichtinvasive Therapieoption mit geringen bis keinen Nebenwirkungen eingesetzt werden, um Schlaf, Stimmung und Allgemeinbefinden zu verbessern. Der vorliegende Beitrag gibt einen Überblick über den aktuellen Wissensstand hinsichtlich der Auswirkungen von Licht auf zirkadiane Rhythmen, Schlaf und Stimmung. Schlüsselwörter Zirkadiane Rhythmen, Natürliches Licht, Künstliches Licht Depression, Lichttherapie  Anatomical architecture of the circadian system The central master-clock in mammalian species, including humans, is the suprachiasmatic nuclei (SCN), a paired structure in the hypothalamus with a volume just about 0.25 mm3 per nucleus (e.g. ). Within the mammalian SCN, a molecular oscillator keeps the clock oscillating at its normal pace. The basis of this oscillator is two interconnected molecular feedback loops of clock gene expression, a detailed description of which is beyond the scope of this review though (see for a detailed explanation). More https://link.springer.com/article/10.1007%2Fs11818-019-00215-x Sleep mask version of the Biointernet Mask Classic About The Biointernet Mask Sleep Mask Digital Download Sleep Now! Translighters Digital Technologies by Sergey Avdeev and Kirill Korotkov Sleep mask version of the Biointernet Mask Classic Download Sleep Now! Translighters Digital Technologies by Sergey Avdeev and Kirill Korotkov The Biointernet Sleep Mask Digital – digital sleep mask version of the Biointernet Mask Classic Shop now The Biointernet Sleep Mask Digital – digital sleep mask version of the Biointernet Mask 9 MB Serial number: 5432 Translighters Digital Technologies – Images, videos, text, web, Social Media and other files with Translighters functions Create Your Own Night Dream Today!

The Biointernet Mask Light effects on circadian rhythm and sleep mask Systematic review of light exposure impact on human circadian rhythm ABSTRACT Light is necessary for life, and artificial light improves visual performance and safety, but there is an increasing concern of the potential health and environmental impacts of light. Findings from a number of studies suggest that mistimed light exposure disrupts the circadian rhythm in humans, potentially causing further health impacts. However, a variety of methods has been applied in individual experimental studies of light-induced circadian impacts, including definition of light exposure and outcomes. Thus, a systematic review is needed to synthesize the results. In addition, a review of the scientific evidence on the impacts of light on circadian rhythm is needed for developing an evaluation method of light pollution, i.e., the negative impacts of artificial light, in life cycle assessment (LCA). The current LCA practice does not have a method to evaluate the light pollution, neither in terms of human health nor the ecological impacts. The systematic literature survey was conducted by searching for two concepts: light and circadian rhythm. The circadian rhythm was searched with additional terms of melatonin and rapid-eye-movement (REM) sleep. The literature search resulted to 128 articles which were subjected to a data collection and analysis. Melatonin secretion was studied in 122 articles and REM sleep in 13 articles. The reports on melatonin secretion were divided into studies with specific light exposure (101 reports), usually in a controlled laboratory environment, and studies of prevailing light conditions typical at home or work environments (21 studies). Studies were generally conducted on adults in their twenties or thirties, but only very few studies experimented on children and elderly adults. Surprisingly many studies were conducted with a small sample size: 39 out of 128 studies were conducted with 10 or less subjects. The quality criteria of studies for more profound synthesis were a minimum sample size of 20 subjects and providing details of the light exposure (spectrum or wavelength; illuminance, irradiance or photon density). This resulted to 13 qualified studies on melatonin and 2 studies on REM sleep. Further analysis of these 15 reports indicated that a two-hour exposure to blue light (460 nm) in the evening suppresses melatonin, the maximum melatonin-suppressing effect being achieved at the shortest wavelengths (424 nm, violet). The melatonin concentration recovered rather rapidly, within 15 min from cessation of the exposure, suggesting a short-term or simultaneous impact of light exposure on the melatonin secretion. Melatonin secretion and suppression were reduced with age, but the light-induced circadian phase advance was not impaired with age. Light exposure in the evening, at night and in the morning affected the circadian phase of melatonin levels. In addition, even the longest wavelengths (631 nm, red) and intermittent light exposures induced circadian resetting responses, and exposure to low light levels (5–10 lux) at night when sleeping with eyes closed induced a circadian response. The review enables further development of an evaluation method of light pollution in LCA regarding the light-induced impacts on human circadian system. KEYWORDS: Light, human health, melatonin, REM sleep, health, circadian rhythm Introduction Artificial light is a necessity in the modern societies. It provides illumination when natural light is not available enabling a multitude of functions after dark. It is intended to improve the visual performance and visibility in indoor and outdoor environments, thus improving safety and comfort of humans. In addition, artificial light may serve as a source for relaxation and beauty, and to improve alertness and productivity. More: https://www.tandfonline.com/doi/full/10.1080/07420528.2018.1527773 The human circadian system in normal and disordered sleep. Abstract The human circadian system regulates rhythmicity in the human body and establishes normal sleep and wake phases. The suprachiasmatic nuclei (SCN), located in the hypothalamus above the optic chiasm, make up the human pacemaker known as the circadian or biological clock, but other essential parts of the circadian system include the pineal gland, retina, and retinohypothalamic tract. The importance of light in resetting the intrinsic human circadian cycle, the intrinsic period of which is slightly longer than 24 hours, ensures that the human cycle will stay entrained to the earth's 24-hour daily cycle. Within the SCN neurons, circadian rhythmicity is generated by the regular transcription of proteins. Since the circadian system is the foundation of the sleep-wake cycle, disorders and abnormalities in sleep are often connected with disorders or abnormalities in the circadian system. Circadian rhythm sleep disorders, such as jet lag syndrome and shift work sleep disorder, are those specifically attributed to dysfunctions or insufficiencies in the circadian system. Taking into consideration the preeminence of the circadian clock in timing sleep, it is likely that other sleep disorders, such as insomnia, are also linked to circadian system abnormalities. More: https://www.ncbi.nlm.nih.gov/pubmed/16336035 Effect of Light on Human Circadian Physiology Synopsis The circadian system in animals and humans, being near but not exactly 24-hours in cycle length, must be reset on a daily basis in order to remain in synchrony with external environmental time. This process of entrainment is achieved in most mammals through regular exposure to light and darkness. In this chapter, we review the results of studies conducted in our laboratory and others over the past 25 years in which the effects of light on the human circadian timing system were investigated. These studies have revealed, how the timing, intensity, duration, and wavelength of light affect the human biological clock. Our most recent studies also demonstrate that there is much yet to learn about the effects of light on the human circadian timing system. Keywords: biological rhythm, core body temperature, illuminance, melatonin, phase response curve

ntroduction