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FLI-1 more time: who's the molecular switch allowing marrow stem cells to expand?
Stem cells are immature cells that have a basic regenerative role in virtually all tissues. They normally exist in a quiescent, slowly dividing state, but after an injury can replace tissue by switching to an activated state in which they multiply rapidly and turn into mature, functional cells. According to a new preclinical study led by Weill Cornell Medicine scientists, a single molecular…
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Innate immunity connected to gut microbiota: the guests teach the host how to behave
Innate immunity connected to gut microbiota: the guests teach the host how to behave
Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract. These rapidly multiplying foreign invaders represent, by far, the biggest threat to the neonatal immune…
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